Results 121 to 130 of about 3,949,769 (293)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
A 7-Bit Vector-Sum Phase Shifter for LEO Satellite Communication in 90-Nm CMOS Process
IEEE AccessThis paper presents a 7-bit vector-sum phase shifter for low-earth-orbit satellite communication. The phase shifter consists of a differential-type quadrature all-pass filter (QAF) and an analog differential vector adder, where a matching network is ...
Hao-Jen Tu +3 more
doaj +1 more source
Vivaldi Antenna Arrays Feed by Frequency-Independent Phase Shifter for High Directivity and Gain Used in Microwave Sensing and Communication Applications. [PDF]
Sensors (Basel), 2021 Ghimire J, Diba FD, Kim JH, Choi DY.
europepmc +1 more source
A wide band sanky phase shifter for phase sensitive detectors
, 1974 The design details of a wide band Sanky phase shifter are given. This phase shifter can be used with phase-sensitive detectors which are required to work with variable reference frequencies.
Sankaranarayanan, PE
core
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Reflection-Type Phase Shifters Using RF-MEMS-Switched Bandpass Filtering Loads
IEEE AccessThis manuscript reports on the design and practical development of reflection-type phase shifters (RTPSs) utilizing RF-switched bandpass filter (BPF)-based reflective loads.
Zehan Guo +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source