Results 111 to 120 of about 7,314,597 (340)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Signatures of unstable semiclassical trajectories in tunneling

, 2009
It was found recently that processes of multidimensional tunneling are generally described at high energies by unstable semiclassical trajectories. We study two observational signatures related to the instability of trajectories.
, A G Panin, Berry M V, Bezrukov F, Bezrukov F Levkov D, Bonini G F Cohen A G Rebbi C Rubakov V A, Creagh S C, Creagh S C, Creagh S C, D G Levkov, Kleinert H, Levkov D G Panin A G, Press W H, Rubakov V A, S M Sibiryakov, Shudo A, Smith G C, Takahashi K, Takahashi K, Takahashi K, Takahashi K, Tomsovic S, Wilkinson M   +22 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Optimum Path Synthesis of a Geared Five-Bar Mechanism

Advances in Mechanical Engineering, 2013
Most studies on path synthesis problems are to trace simple or smooth trajectories. In this work, an optimum synthesis for several special trajectories generated by a geared five-bar mechanism is studied using the one-phase synthesis method.
Wen-Yi Lin
doaj   +1 more source

Trajectory Generation from Motion Capture for a Planar Biped Robot in Swing Phase

Ingeniería y Ciencia, 2015
This paper proposes human motion capture to generate movements for the right leg in swing phase of a biped robot restricted to the sagittal plane. Such movements are defined by time functions representing the desired angular positions for the joints ...
Diego A Bravo, Carlos F Rengifo R
doaj   +1 more source

Gait Trajectory and Gait Phase Prediction Based on an LSTM Network

Sensors, 2020
Lower body segment trajectory and gait phase prediction is crucial for the control of assistance-as-needed robotic devices, such as exoskeletons. In order for a powered exoskeleton with phase-based control to determine and provide proper assistance to ...
Binbin Su, Elena M. Gutierrez-Farewik
doaj   +1 more source

Calibration of atomic trajectories in a large-area dual-atom-interferometer gyroscope

, 2017
We propose and demonstrate a method for calibrating atomic trajectories in a large-area dual-atom-interferometer gyroscope. The atom trajectories are monitored by modulating and delaying the Raman transition, and they are precisely calibrated by ...
Li, Run-Bing, Lu, Si-Bin, Luo, Jun, Wang, Jin, Yao, Zhan-Wei, Zhan, Ming-Sheng   +5 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

STABILITY OF THE REST POINTS FRACTIONAL OSCILLATOR FITZHUGH-NAGUMO

Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2019
In this paper, using the qualitative analysis, we studied the stability of the point of rest of the fractional oscillator FitzHugh-Nagumo in commensurate and incommensurable cases.
O. D. Lipko
doaj   +1 more source

Phase Plane Trajectories of the Muscle Spike Potential

Biophysical Journal, 1963
To facilitate a study of the transmembrane action current, the striated muscle spike potential was recorded against its first time derivative. The specialized recording methods are described, as well as several mathematical transformations between a coordinate system in V, t, and the present coordinate system in V, dV/dt.
openaire   +2 more sources