Results 101 to 110 of about 789,262 (344)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Observing the phase space trajectory of an entangled matter wave packet

, 2010
We observe the phase space trajectory of an entangled wave packet of a trapped ion with high precision. The application of a spin dependent light force on a superposition of spin states allows for coherent splitting of the matter wave packet such that ...
Poschinger, Ulrich, Schmidt-Kaler, Ferdinand, Singer, Kilian, Walther, Andreas   +3 more
core   +1 more source

Phase Plane Trajectories of the Muscle Spike Potential

Biophysical Journal, 1963
To facilitate a study of the transmembrane action current, the striated muscle spike potential was recorded against its first time derivative. The specialized recording methods are described, as well as several mathematical transformations between a coordinate system in V, t, and the present coordinate system in V, dV/dt.
openaire   +2 more sources

Phased Flight Trajectory Prediction with Deep Learning

, 2022
20 pages, 9 ...
Zhang, Kai, Chen, Bowen
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Multi-stage global trajectory optimization for the overlapping shift of a seamless two-speed transmission using Legendre pseudo-spectral method

Advances in Mechanical Engineering, 2017
For a seamless two-speed transmission specially equipped in electric vehicles, the global trajectory optimization problem of the overlapping shift process with multiple stages and complex path/point constraints is investigated in this article.
Jie Ye, Kegang Zhao, Yanwei Liu, Xiangdong Huang, Huibin Lin   +4 more
doaj   +1 more source

Crossover scaling functions and an extended minimal subtraction scheme

, 1995
A field theoretic renormalization group method is presented which is capable of dealing with crossover problems associated with a change in the upper critical dimension.
Aharony, Aharony, Ahlers, Amit, Amit, Benzoni, Brezin, Cardy, Erwin Frey, Fisher, Freire, Frey, Frey, Frey, Frey, Frey, Frowein, Kinzel, Larkin, Lawrie, Lawrie, Nattermann, Nelson, O'Connor, O'Connor, O'Connor, O'Connor, O'Connor, Pfeuty, Riedel, Riedel, Riedel, Schloms, Schloms, Schwabl, Stauffer, Täuber, Täuber, Uzunov   +38 more
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Characterization of a spring pendulum phase-space trajectories

Chaos: An Interdisciplinary Journal of Nonlinear Science
We study the geometrical properties of phase-space trajectories (or orbits) of a spring pendulum as functions of the energy. Poincaré maps are used to describe the properties of the system. The points in the Poincaré maps of regular orbits (non-chaotic) cluster around separated segments or in chains of islands.
Karla P. Acosta-Zamora, José Núñez González, Ahtziri González, Eduardo Ramos   +3 more
openaire   +2 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source