Results 161 to 170 of about 562,206 (315)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Design concept and phase transformation study of advanced bainitic-austenitic medium-Mn steel. [PDF]

Sci Rep
Wojtacha A, Kozłowska A, Skowronek A, Gulbay O, Opara J, Gramlich A, Matus K.   +6 more
europepmc   +1 more source

Nonequilibrium phase transformations in alloys subjected to severe plastic deformation

, 2019
I. K. Razumov, Anatoly Ye. Yermakov, Yurii N. Gornostyrev, Boris B. Straumal   +3 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Can Non-Phase-Transformation Heat Treatments Improve the Strength Properties of Materials? [PDF]

Materials (Basel)
Neacșa A, Ramadan IN, Diniță A, Iacob ȘV, Ilincă CN, Laudacescu EV.   +5 more
europepmc   +1 more source

Ultra-high-strain-rate deformation induced HCP-to-FCC phase transformation and its interaction with {112¯2} twin in pure Ti

Liu, Qian, Zhou, Bohao, Zhang, Xing, Wang, Yuqian, Sun, Wanting, Zhang, Qifei, Wang, Yafei, Liang, Gaofei, Wang, Hao, Chu, Shuangjie, Mao, Bo   +10 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Atomic Imaging of Phase Transformation and Self-Intercalation of Two-Dimensional CrS₂ by <i>In Situ</i> TEM. [PDF]

ACS Appl Mater Interfaces
Chou PY, Sung HY, Wang CH, Huang CW, Wu WW.   +4 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Surface Reconstruction in Quasi-2D Perovskite Films Treated with Cesium Halide Nanocrystals: Halide Exchange or Phase Transformation. [PDF]

Small Sci
Son DI, Min S, An S, Lee D, Lee SH, Kim D, Song MH, Kim JY, Park S, Cho J, Park J.   +10 more
europepmc   +1 more source