Results 171 to 180 of about 562,206 (315)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Phase transformation temperatures influence the reduction ratio of fatigue resistance of nickel-titanium reciprocating files at body temperature: an in vitro experimental study. [PDF]

Restor Dent Endod
Nehme W, Naaman A, Pedèches L, Lê S, Georgelin-Gurgel M, Kwak SW, Kim HC, Diemer F.   +7 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

A Study on Thermally Fatigued Phase Transformation and Bending Fracture Mechanisms of 310S Stainless Steel. [PDF]

Materials (Basel)
Huang YT, Yen YW, Hung FY.
europepmc   +1 more source

Polymorphism and phase transformations of a cocrystal of nicotinamide and pimelic acid

, 2012
Srinivasulu Aitipamula, Annie B. H. Wong, Pui Shan Chow, Reginald B. H. Tan   +3 more
openalex   +2 more sources

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Effects of Temperature and Random Forces in Phase Transformation of Multi-Stable Systems. [PDF]

Entropy (Basel)
Florio G, Giordano S, Puglisi G.
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Microstructure, phase transformation temperatures and long-term stability of ex-situ Alloy 718 + TiB₂ metal-ceramic nanocomposites as a repair coatings for aerospace applications. [PDF]

Sci Rep
Rakoczy Ł, Grudzień-Rakoczy M, Cempura G, Kargul T, Rząd E, Madej M, Kruk A, Dudziak T, Kozień D, Cygan R, Chulist R, Galusek D.   +11 more
europepmc   +1 more source

HRTEM Studies of Phase Transformation in Boron Nitride Under High Pressure And High Temperature [PDF]

, 2003
Jianyu Huang
openalex   +1 more source