Results 191 to 200 of about 9,741,578 (338)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Direct Observation of Structural Phase Transformations during Phosphorene Formation on Cu(111). [PDF]

open access: yesACS Nano
David J   +8 more
europepmc   +1 more source

Crystallographic Features of Phase Transformations during the Continuous Cooling of a Ti6Al4V Alloy from the Single-Phase β-Region. [PDF]

open access: yesMaterials (Basel), 2022
Naschetnikova IA   +5 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Glass-Ceramics of the Lithium Aluminosilicate System Nucleated by TiO2: The Role of Redox Conditions of Glass Melting in Phase Transformations and Properties. [PDF]

open access: yesMaterials (Basel)
Maltsev S   +9 more
europepmc   +1 more source

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