Results 151 to 160 of about 1,033,856 (318)
Phase Transition in Ant Colony Optimization
PhysicsAnt colony optimization (ACO) is a stochastic optimization algorithm inspired by the foraging behavior of ants. We investigate a simplified computational model of ACO, wherein ants sequentially engage in binary decision-making tasks, leaving pheromone ...
Shintaro Mori +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
International Journal of Nanomedicine, 2023 Shihui Guan, Dengke Teng, Hui Wang,* Qimeihui Wang,* Xi Zhen, Guoqing Sui, Yang Wang, Lingyu Zhu, Yuanqiang Lin, Dan Jiao, Feng Guo Department of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, 130033 ...
Guan S +10 more
doaj
Fluctuations At Phase Transitions
, 1994 We use the closed time-path formalism to calculate fluctuations at phase transitions, both in and out of equilibrium. Specifically, we consider the creation of vortices by fluctuations, of relevance to the early universe and to $^{4}He$ superfluidity. (Invited talk to Nato Advanced Research Workshop on Electroweak Physics and the Early Universe, Sintra
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
PHASE TRANSITIONS AT INTERFACES
Le Journal de Physique Colloques, 1989 The interface between two phases may exhibit significant structural changes if one of them comes close to a phase transition in its bulk. Surface critical phenomena, critical adsorption, and wetting phenomena, like e.g. surface melting or surface induced disorder, can occur.
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FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source