Results 201 to 210 of about 1,033,856 (318)

Reprogrammable Phase-Transition Composites for Adaptive Dynamic Shape Morphing. [PDF]

Adv Sci (Weinh)
Zhong Y, Tang W, Guo X, Qin K, Zhu P, Sheng Q, Wang Y, Yang H, Zou J.   +8 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Rheo-Impedance Measurements of Lamellar-Vesicular Phase-Transition Behavior. [PDF]

ACS Omega
Shitanda I, Kotsubo R, Hashiba C, Loew N, Yamagata Y, Miyamoto K, Ogura T, Watanabe H, Itagaki M.   +8 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Correlative Ultrafast Imaging of a Photodriven Phase Transition Using 4D Scanning Transmission Electron Microscopy. [PDF]

ACS Nano
Niedermayr A, Wu J, Fisher B, Kaminer I, Weissenrieder J.   +4 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Phase transitions in project scheduling. [PDF]

The analysis of the complexity of combinatorial optimization problems has led to the distinction between problems which are solvable in a polynomially bounded amount of time (classified in P) and problems which are not (classified in NP).
De Reyck, B, Herroelen, Willy
core  

Non-reciprocal spin excitations across the skyrmion-paramagnetic phase transition in MnSi. [PDF]

J Appl Crystallogr
Weber T, Schmalzl K, Waizner J, Bauer A, Garst M, Pfleiderer C.   +5 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

NUCLEAR LIQUID-GAS PHASE TRANSITION: EXPERIMENTAL SIGNALS [PDF]

, 2005
G. Casini, BRUNO, MAURO, VANNINI, GIANNI, Nuclear Physics A. 749 55c 6.4.c., F. Cannata, D'AGOSTINO, MICHELA, GERACI, ELENA IRENE, NUCLEAR LIQUID GAS PHASE TRANSITION: EXPERIMENTAL SIGNALS, A. Moroni, F. Gulminelli, F. Gramegna, P.h. Chomaz   +11 more
core   +1 more source