Results 151 to 160 of about 255,155 (268)

Density Functional Theory and Information-Theoretic Diagnostics of Quantum Phase Transitions. [PDF]

Entropy (Basel)
Romera E, Nagy Á.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

An Atom-Precise Approach to Damp First-Order Phase Transitions and Its Implications for Neuromorphic Signal Processing. [PDF]

J Am Chem Soc
Agbeworvi G, Kumar N, Ponis JD, Hariyani S, Jerla N, Jardali F, Li J, Zaheer W, Handy JV, Ayala JR, Jaye C, Weiland C, Fischer DA, Shamberger PJ, Guo J, Williams RS, Sambandamurthy G, Banerjee S.   +17 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Experimental observation of non-Hermitian phase transitions using laser-induced thermoacoustics. [PDF]

Nat Commun
Zhang H, Fan R, Xiong W, Sun K, Zhang A, Zhang Z, Shao C, Ma C, Bai Y, Cheng Y, Peng R, Liu X, Christensen J.   +12 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Comparative study of structural stability in [NH4−n (CH3)n]2HgCl4 and in related compounds

Open Chemistry, 2004
Amami M., Salah A.
doaj   +1 more source

In situ electron diffraction tomography study of the successive phase transitions in LaTaO₄ nanocrystals. [PDF]

Nat Commun
Wu S, Peng C, Zhou W, Morrison FD, Howieson GW, Ma Y.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Tree Tensor Network Simulation of Dynamical Quantum Phase Transitions in the 2D Transverse-Field Ising Model. [PDF]

Entropy (Basel)
Zhang X, Xie D, Li Y.
europepmc   +1 more source