Results 201 to 210 of about 9,597,779 (345)

Impact of Single-Particle Compressibility on the Fluid-Solid Phase Transition for Ionic Microgel Suspensions [PDF]

, 2015
Miguel Peláez-Fernández, Anton Souslov, L. Andrew Lyon, Paul M. Goldbart, Alberto Fernández‐Nieves   +4 more
openalex   +1 more source

Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets

Cell, 2017
Yongdae Shin, Joel D. Berry, N. Pannucci, M. Haataja, Jared E. Toettcher, C. Brangwynne   +5 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Cluster Formation and Phase Transitions Induced by Vibrational Strong Coupling. [PDF]

Angew Chem Int Ed Engl
Sandeep K, Swaminathan S, Jayachandran A, Nagarajan K, Gautier J, Kushida S, Chervy T, Vergauwe RMA, Thomas A, Ebbesen TW.   +9 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Phase-programmed immunoengineering: dual-functional nanofibrous scaffold with spatiotemporal Cu-Mg release for anti-infection to pro-repair transition in wounds

Zhenjiang Zech Xu, Shicheng Huo, Yifan Zhang, Weiwei Lin, Jia Liu, Xiaojuan Wen, Yifei Liu, Changgui Shi, Guohua Xu   +8 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Nature of Temperature-Induced Phase Transitions in Secondary Organic Aerosol Particles. [PDF]

Environ Sci Technol
Jensen LN, Kristensen K, Iversen EM, Canagaratna MR, Roldin P, Bilde M.   +5 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Superstructural phase transitions in polymer-grafted nanooctahedra. [PDF]

Sci Adv
Zhu B, Chen J, Li R, Ren J, Wang Y, Zhong Y, Liu Y, Yasuhara A, Kakefuda M, Aoyama Y, Vo T, Ye X.   +11 more
europepmc   +1 more source