Results 111 to 120 of about 1,240,122 (231)

Review of Chagas Disease and Treatment Obstacles to Eradication [PDF]

open access: yes, 2019
The World Health Organization and the Center for Disease Control reports Chagas disease, or American trypanosomiasis, as a major neglected tropical disease prevalent in 21 endemic Latin American countries.
Sherman, Emily
core   +1 more source

Emergency Stroke Calls: Obtaining Rapid Telephone Triage (ESCORTT) - a programme of research to facilitate recognition of stroke by emergency medical dispatchers [PDF]

open access: yes, 2014
Background: Rapid access to emergency stroke care can reduce death and disability by enabling immediate provision of interventions such as thrombolysis, physiological monitoring and stabilisation.
  +61 more
core   +1 more source

Clinical proteomic biomarkers: relevant issues on study design & technical considerations in biomarker development

open access: yesClinical and Translational Medicine, 2014
Biomarker research is continuously expanding in the field of clinical proteomics. A combination of different proteomic–based methodologies can be applied depending on the specific clinical context of use.
Maria Frantzi   +2 more
doaj   +1 more source

Gender differences in clinical registration trials: is there a real problem?

open access: yesBritish Journal of Clinical Pharmacology, 2018
Aims Several studies have reported the under‐representation of women in clinical trials, thereby challenging the external validity of the benefit/risk assessments of launched drugs. Our aim was to determine the extent to which women have been included in
Geert Labots   +4 more
semanticscholar   +1 more source

Relationship between primary liver hepatocellular carcinoma volumes on portal-venous phase CT imaging [PDF]

open access: yes, 2016
The liver is an important organ in the body. It is located under the rib cage on the right side. The liver performs many important functions, it processes food for nutrients that the body requires and also helps in the detoxification of harmful materials.
Aisaborhale, Ehimen Edward
core   +1 more source

The PCORI Engagement Rubric: Promising Practices for Partnering in Research

open access: yesAnnals of Family Medicine, 2017
PURPOSE Engaging patients, caregivers, and other health care stakeholders as partners in planning, conducting, and disseminating research is a promising way to improve clinical decision making and outcomes.
S. Sheridan   +4 more
semanticscholar   +1 more source

Improving Participant Recruitment in Clinical Trials: Comparative Analysis of Innovative Digital Platforms

open access: yesJournal of Medical Internet Research
BackgroundPharmaceutical product development relies on thorough and costly clinical trials. Participant recruitment and monitoring can be challenging.
Alexia Georgia Bikou   +7 more
doaj   +1 more source

Validation of the recording of acute exacerbations of COPD in the clinical practice research datalink: Phase 1 results

open access: yes6.1 Epidemiology, 2015
Background: The Clinical Practice Research Datalink (CPRD) is a UK database of primary care health records covering 11 million residents of England and Wales, including at least 200000 COPD patients. We aimed to validate the recording of acute exacerbations of COPD (AECOPD).
Rothnie, KJ   +6 more
openaire   +2 more sources

Successful development and clinical translation of a novel anterior lamellar artificial cornea

open access: yesJournal of Tissue Engineering and Regenerative Medicine, 2019
Blindness due to corneal diseases is a common pathology affecting up to 23 million individuals worldwide. The tissue‐engineered anterior human cornea, which is currently being tested in a Phase I/II clinical trial to treat severe corneal trophic ulcers ...
Laura Rico-Sánchez   +20 more
semanticscholar   +1 more source

Towards an Architecture to Guarantee Both Data Privacy and Utility in the First Phases of Digital Clinical Trials

open access: yesSensors, 2018
In the era of the Internet of Things (IoT), drug developers can potentially access a wealth of real-world, participant-generated data that enable better insights and streamlined clinical trial processes.
Fabio Angeletti   +2 more
doaj   +1 more source

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