Results 41 to 50 of about 1,240,122 (231)

Where is clinical research for radiotherapy going? Cross-sectional comparison of past and contemporary phase III clinical trials [PDF]

open access: yesRadiation Oncology, 2020
Abstract Purpose The features of past and contemporary phase III clinical trials for radiotherapy were reviewed to activate future clinical trials and to advise on actual clinical practice. Methods and materials The phase III clinical trials for radiotherapy were searched in
Sunmin Park, Chai Hong Rim, Won Sup Yoon
openaire   +3 more sources

Guidance on interim analysis methods in clinical trials

open access: yesJournal of Clinical and Translational Science, 2023
Interim analyses in clinical trials can take on a multitude of forms. They are often used to guide Data and Safety Monitoring Board (DSMB) recommendations to study teams regarding recruitment targets for large, later-phase clinical trials.
J. Ciolino, A. Kaizer, L. Bonner
semanticscholar   +1 more source

Autologous blood clots: a natural biomaterial for wound healing

open access: yesFrontiers in Materials, 2023
Repair after injury in mammalian tissue involves a complex cascade of events, with the formation of local blood clots being essential for the initial phases of wound healing.
David M. Richter   +5 more
doaj   +1 more source

Pain perception and migraine [PDF]

open access: yes, 2018
Background: It is well-known that both inter-and intra-individual differences exist in the perception of pain; this is especially true in migraine, an elusive pain disorder of the head.
Coppola, Gianluca   +6 more
core   +1 more source

Methodological Issues in Randomized Clinical Trials for Prodromal Alzheimer's and Parkinson's Disease

open access: yesFrontiers in Neurology, 2021
Alzheimer's disease (AD) and Parkinson's disease (PD) are the first and second most common neurodegenerative disorders, respectively. Both are proteinopathies with inexorable courses and no approved disease-modifying therapies.
Camila Henriques de Aquino   +2 more
doaj   +1 more source

Dissociation and interpersonal autonomic physiology in psychotherapy research: an integrative view encompassing psychodynamic and neuroscience theoretical frameworks [PDF]

open access: yes, 2016
Interpersonal autonomic physiology is an interdisciplinary research field, assessing the relational interdependence of two (or more) interacting individual both at the behavioral and psychophysiological levels.
Benelli, Enrico   +3 more
core   +1 more source

Recurrent Hypocalcemic Tetany as the Initial Presentation in Some Persons with Hyperthyroidism: A Case Series

open access: yesDubai Diabetes and Endocrinology Journal, 2021
This is a case series of recurrent hypocalcemic tetany as the initial presentation in some cases of hyperthyroidism. Literature review has revealed more reports of hypercalcemia than hypocalcemia as a feature of hyperthyroidism.
Yakubu Lawal   +3 more
doaj   +1 more source

Assessing the Clinical Robustness of Digital Health Startups: Cross-sectional Observational Analysis

open access: yesJournal of Medical Internet Research, 2022
Background The digital health sector has experienced rapid growth over the past decade. However, health care technology stakeholders lack a comprehensive understanding of clinical robustness and claims across the industry.
S. Day   +4 more
semanticscholar   +1 more source

The TOSCA Registry for Tuberous Sclerosis-Lessons Learnt for Future Registry Development in Rare and Complex Diseases. [PDF]

open access: yes, 2019
Introduction: The TuberOus SClerosis registry to increase disease Awareness (TOSCA) is an international disease registry designed to provide insights into the clinical characteristics of patients with Tuberous Sclerosis Complex (TSC).
Beaure d'Augères, Guillaume   +29 more
core   +2 more sources

Dose translation between laboratory animals and human in preclinical and clinical phases of drug development

open access: yesDrug development research (Print), 2018
Preclinical Research ...
Anroop B Nair, M. Morsy, S. Jacob
semanticscholar   +1 more source

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