Results 111 to 120 of about 7,565,239 (380)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Multiplexed bioluminescence microscopy via phasor analysis
Nature Methods, 2021 Zi Yao +6 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Research on the Protection System for Smart Grid Based on Phasor Information at Circuit Breakers
EnergiesA smart grid protection system based on phasor information at circuit breakers is proposed in this paper. Phasor data for fault diagnosis is obtained from phasor measurement units or intelligent electronic devices installed near circuit breakers, without
Yi Liu, Ding Dang, Seon-Keun Lee
doaj +1 more source
Squeezed Optomechanics with Phase-Matched Amplification and Dissipation [PDF]
, 2015 Xin‐You Lü +5 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Least-squares Fourier phase estimation from the modulo 2Pi bispectrum phase [PDF]
, 1991 The recovery of Fourier phases from measurements of the bispectrum occupies a vital role in many astronomical speckle imaging schemes. In arecent paper [J. Opt. Soc. Am.
Haniff, Christopher A.
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