Results 71 to 80 of about 1,369 (260)
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
This paper proposes an optimal control scheme based on a synchronized phasor (synchrophasor) for power system secondary voltage control. The framework covers voltage stability monitoring and control.
Heng-Yi Su, Yi-Chung Chen, Yu-Liang Hsu
doaj +1 more source
Parameter estimation based on the measurement data of the phasor measurement unit (PMU) is an important approach for identifying the Thévenin equivalent parameters (TEPs) of power systems. However, in the process of acquiring or transmitting data in PMU,
Anan Zhang +3 more
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Modified recurrent equation-based cubic spline interpolation for missing data recovery in phasor measurement unit (PMU). [PDF]
Thangaraj S, Goh VT, Yap TTV.
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Optimal placement of Phasor Measurement Unit considering System Observability Redundancy Index: case study of the Kenya power transmission network. [PDF]
Okendo EO, Wekesa CW, Saulo MJ.
europepmc +1 more source

