Results 151 to 160 of about 54,390 (269)

Modulation of Tau Protein Neurotoxic Hallmarks by Novel σ1R Agonists/HDAC Inhibitor Dual‐Acting Compounds

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
This study explores the development of dual‐acting compounds combining σ1R agonists and histone deacetylase inhibitors (HDACi). Key findings include compound 2d and 3a's high affinity for σ1R and favorable pharmacokinetic profile and an in vivo determined σ1R agonist profile by reversing the effect of the σ1R antagonist BD‐1063.
Antonino N. Fallica   +16 more
wiley   +1 more source

Natural Antioxidants as Thermal Stabilizers in Fully Biobased PHBV Compounds

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 9, March 5, 2026.
Polyhydroxyalkanoates (PHA) are promising biobased polymers but degrade easily under heat and oxygen. This study examines PHBV with natural antioxidants to enhance thermal stability during processing. Results show regenerative additives prevent degradation and the effectiveness is comparable to that of synthetic additives.
Ann‐Christin Rusko   +3 more
wiley   +1 more source

A Tracer Diffusion Study of Diverse Photo‐Ionic Phenomena in Strontium Titanate

open access: yesAdvanced Functional Materials, Volume 36, Issue 22, 16 March 2026.
Two strong interfacial photo‐ionic effects are demonstrated for the model system SrTiO3 through the application of isotope exchange experiments: UV illumination is found to enhance the oxygen surface exchange coefficient by several orders of magnitude and to depress the surface space‐charge potential substantially.
David M. Schwenkel   +3 more
wiley   +1 more source

The THOR network best practices for females of childbearing potential with life‐threatening hemorrhage: Guidance for emergency medical services and hospitals

open access: yes
Transfusion, EarlyView.
Matthew J. Levy   +12 more
wiley   +1 more source

Dual‐Interface Engineering of the Source Electrode to Overcome the Intrinsic Injection‐Leakage Trade‐Off in Organic Schottky Barrier Transistors

open access: yesAdvanced Functional Materials, Volume 36, Issue 23, 19 March 2026.
A charge injection layer is introduced via RIE to decouple the dual functions of the source electrode: lowering contact resistance through doping to enhance charge injection, while SAM modification on the top surface minimizes leakage current. This strategy enables OSBTs to achieve a high on/off ratio with improved stability and performance.
Hye Ryun Sim   +6 more
wiley   +1 more source

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