Results 61 to 70 of about 4,198,057 (378)
Nucleic Acids Research, 2018 Histone post–translational modifications regulate chromatin structure and function largely through interactions with effector proteins that often contain multiple histone-binding domains.
Ruiqiong Liu +15 more
semanticscholar +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
the Study of some pro- inflammatory and Anti –inflammatory interleukins in diabetic patients
Academic Science JournalObjective; The objective of present research is evaluation roles of IL-38 and IL-39 indicators in pathophysiology of diabetic mellitus type II. Methods; The conducted investigation was occurred inside Bagdad capital during time period 1/8 to
enaas saad +2 more
doaj +1 more source
Creating Online Lessons: A Faculty Development Seminar Series [PDF]
, 2003 The World Wide Web is being used increasingly to deliver instruction in medical education. Consequently, there is a need to train faculty in developing and implementing online instruction. We developed and implemented a seminar series to teach faculty to
Reznich , PhD, Christopher +3 more
core
A Survey and a Positive Psychology Intervention on French PhD Student Well-being
, 2018 Aim/Purpose The present work focuses on French PhD students’ well-being: an understudied working population thus far, which impedes the development of evidence-based policies on this issue in France.
Gabriel A B Marais +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
A Study on the Rate of Articles Derived from PhD Dissertations in University of Tehran (2001-2005) [PDF]
تحقیقات کتابداری و اطلاعرسانی دانشگاهی, 2010 Objective: The present study primarily aims to shed a light on the rate of papers derived from the PhD Theses concluded in the University of Tehran during the 2001-2005 Period.
Keyvan Kousha +3 more
doaj
Acquiring a doctoral degree: was it worth it?
Future Science OA, 2020 When I started my doctoral degree a couple of years ago at the University of Tasmania in Australia, my enthusiasm for starting a doctoral degree with a scholarship was very high; however, along the way, due to various challenges, I began to ask myself ...
Olumide A Odeyemi
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Bilgi Dünyası, 2018 The Ukrainian library and information science/studies (LIS) accumulated many problems that impede the quality training of library staff. In the process of reforming education and science in Ukraine, several initiatives have been implemented at the ...
Serhii Nazarovets, Maryna Nazarovets
doaj +1 more source