Results 61 to 70 of about 4,018,528 (325)
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
EMBO reports, 2012 Navigating the perils and pitfalls of a PhD is no easy task. This concise survival guide should help budding scientists avoid the most common mistakes and enjoy their first taste of real research.
de Almeida Souza, Leonardo +1 more
openaire +3 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Identification of novel PHD-finger genes in pepper by genomic re-annotation and comparative analyses
BMC Plant Biology, 2022 Background The plant homeodomain (PHD)-finger gene family that belongs to zinc-finger genes, plays an important role in epigenetics by regulating gene expression in eukaryotes. However, inaccurate annotation of PHD-finger genes hinders further downstream
Ji-Yoon Guk +2 more
doaj +1 more source
Cell Metabolism, 2019 The discovery of prolyl hydroxylase domain proteins (PHDs) as key enzymes in the hypoxia inducible factor (HIF) pathway has been followed by reports of a multitude of non-HIF substrates of PHD. Reporting in eLife, Cockman et al. (2019) find a surprising lack of detectable PHD activity toward any of them.
openaire +2 more sources
Tolkien, Eucatastrophe, and the Re-Creation of Medieval Legend [PDF]
, 2017 Using comparative literary analysis, this essay examines three case studies from J.R.R. Tolkien’s oeuvre, in which Tolkien practiced eucatastrophic rewriting: his folk-tale, “Sellic Spell,” in which he re-creates the Old English poem Beowulf; his poem ...
Beal, Jane, PhD
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Thinking Beyond the Scroll: The Ancient Library at Alexandria
, 2011 The ancient library at Alexandria, Egypt became a unique institution, influenced by Aristotle’s school in Athens and the Greek model of learning. The institution consisted of a museum, which functioned as a learning center, and a library collection.
Franz, PhD, Gerald
core +1 more source
Pandemic lockdown must fail: Save lives without crippling the economy [PDF]
, 2020 In the following working paper, I want to make a plea for what I am calling a “reverse quarantine”—quarantining people who are over 65 (who number 52 million), before they get sick.
Hirschhorn, PhD, Larry
core +1 more source
FEBS Open Bio, EarlyView.NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source