Results 91 to 100 of about 4,010 (219)

Microcrystalline testing used in combination with Raman micro-spectroscopy for absolute identification of novel psychoactive substances [PDF]

, 2016
Two new psychoactive substances, namely 4-methylmethcathinone (mephedrone) and 5,6-methylenedioxy-2-aminoindane (MDAI) were analysed with a novel combination of microcrystalline tests followed by Raman micro-spectroscopy to facilitate their absolute ...
Aakeröy, Abdel-Hay, Al-Hossaini, Assi, Assi, Awad, Baron, Belal, Choodum, Christie, Cumba, Cuypers, Davis, Donahue, Elie, Elie, Elie, Emanuel, Fulton, Gallagher, Gibbons, Isaacs, Jones, Lobo Vicente, Mabbott, Mabbott, Mabbott, Maher, Nic Daeid, Nichols, O'Neal, Power, Smith, Smith, Smith, Socrates, Steiner, Tan, Tsumura, Vishweshwar, White, Wood, Wood, Wood, Wood, Zuway   +45 more
core   +3 more sources

Novel Flurbiprofen Derivatives as Antioxidant and Anti-Inflammatory Agents: Synthesis, In Silico, and In Vitro Biological Evaluation

Molecules
In this study, we present the synthesis of five novel compounds by combining flurbiprofen with various substituted 2-phenethylamines. The synthesized derivatives underwent comprehensive characterization using techniques such as 1H- and 13C-NMR ...
Iliyan Ivanov, Stanimir Manolov, Dimitar Bojilov, Gabriel Marc, Diyana Dimitrova, Smaranda Oniga, Ovidiu Oniga, Paraskev Nedialkov, Maria Stoyanova   +8 more
doaj   +1 more source

Novel tetrahydronaphthalen-1-yl-phenethyl ureas: synthesis and dual antibacterial-anticancer activities

Journal of Enzyme Inhibition and Medicinal Chemistry
Cancer and antibiotic-resistant bacterial infections are significant global health challenges. The resistance developed in cancer treatments intensifies therapeutic difficulties.
Yusuf Akbaba, Fatma Necmiye Kacı, Mehmet Enes Arslan, Süleyman Göksü, Adil Mardinoğlu, Hasan Türkez   +5 more
doaj   +1 more source

Bond-additive Modeling. 3. Comparison between the Product-connectivity Index and Sum-connectivity Index [PDF]

, 2010
Using the framework of a previously defined procedure (Refs. 16 and 17), we compared the Randic (product-)connectivity index and the sum-connectivity index for the benchmark sets of molecules, that is, 18 octanes, 82 polycyclic aromatic hydrocarbons, 209
Trinajstić, Nenad, Vukičević, Damir
core   +1 more source

Structure elucidation of nanogram quantities of unknown designer drugs based on phenylalkylamine derivates by ion trap multiple mass spectrometry [PDF]

, 2018
Multiple mass spectra (MS1 to MS6) of 55 phenylalkylamine derivatives were recorded with ion-trap mass spectrometry employing electrospray (ESI) and atmospheric pressure chemical ionization (APCI).
Kölliker, Stephan, Oehme, Michael
core  

Investigating the appearance of new psychoactive substances in South Australia using wastewater and forensic data. [PDF]

, 2018
New psychoactive substances (NPS) have increased in use and popularity worldwide. Wastewater analysis has been successfully applied to evaluate illicit drugs use within a population.
Bade, Richard, Bijlsma, Lubertus, Celma, Alberto, Gerber, Cobus, Hernandez, Felix, Painter, Ben, Stockham, Peter, White, Jason   +7 more
core   +1 more source

A QSAR-based application for the prediction of lethal blood concentration of new psychoactive substances

Emerging Trends in Drugs, Addictions, and Health
The rapid development and introduction of new psychoactive substances (NPS) into illegal markets present an enormous challenge for forensic toxicologists, as there is limited knowledge about their toxicity in humans. To strengthen forensic interpretation
Tarcisio Correa, Jéssica Sales Barbosa, Thiara Vanessa Barbosa da Silva, Thiala Soares Josino da Silva Parente, Danielle de Paula Magalhães, Wanderley Pinheiro Holanda Júnior   +5 more
doaj   +1 more source

Presentations to an urban emergency department in Bern, Switzerland associated with acute recreational drug toxicity [PDF]

, 2017
Although the recreational use of psychoactive substances is common there is only limited systematic collection of data on acute drug toxicity or hospital presentations.
Adrian Stoller, Aristomenis K. Exadaktylos, Evangelia Liakoni, Matthias E. Liechti, Meret Ricklin, Sabine Müller   +5 more
core   +2 more sources

Analytical characterization of bioactive N-benzyl-substituted phenethylamines and 5-methoxytryptamines [PDF]

RationaleSubstances based on the N-(2-methoxybenzyl)phenethylamine template ('NBOMe' derivatives) play an important role in medicinal research but some of these derivatives have also appeared as 'research chemicals' for recreational use which has ...
Brandt, SD, Dempster, NM, Elliott, SP, Kavanagh, PV, Maurer, HH, Meyer, MR, Nichols, DE   +6 more
core   +1 more source

5-HT2 receptor binding, functional activity and selectivity in N-benzyltryptamines.

PLoS ONE, 2019
The last fifteen years have seen the emergence and overflow into the drug scene of "superpotent" N-benzylated phenethylamines belonging to the "NBOMe" series, accompanied by numerous research articles.
Miguel Toro-Sazo, José Brea, María I Loza, Marta Cimadevila, Bruce K Cassels   +4 more
doaj   +1 more source