Results 41 to 50 of about 4,010 (219)

Mechanistic Insights into the Neurotoxicity of 2,5-Dimethoxyphenethylamines (2C) and Corresponding N-(2-methoxybenzyl)phenethylamine (NBOMe) Drugs

open access: yesJournal of Xenobiotics
Substituted phenethylamines including 2C (2,5-dimethoxyphenethylamines) and NBOMe (N-(2-methoxybenzyl)phenethylamines) drugs are potent psychoactive substances with little to no knowledge available on their toxicity.
Eva Gil-Martins   +9 more
doaj   +1 more source

Receptores imidazolínicos. Revisão histórica e estado actual dos conhecimentos.

open access: yesActa Médica Portuguesa, 1993
After the initial demonstration, by Ruffolo in 1977, that imidazolines and phenethylamines do not interact in the same manner with adrenoceptors, a different class of receptors (imidazoline-preferring receptors) was identified.
D Moura
doaj   +1 more source

Simultaneous Determination and Stability Analysis of Ten New Psychoactive Substances including Synthetic Cathinones, Phenethylamines, and Ketamine Substitutes in Urine Using Liquid Chromatography-Tandem Mass Spectrometry

open access: yesInternational Journal of Analytical Chemistry, 2023
Knowing the stability of drugs is important to ensure accurate and reliable results of drug concentrations. This study evaluated the stability of ten new psychoactive substances (NPSs) in urine and methanol/water at different storage temperatures ...
Feng-Shuo Yang   +7 more
doaj   +1 more source

Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens [PDF]

open access: yes, 2016
The present study investigated interactions between the novel psychoactive tryptamines DiPT, 4-OH-DiPT, 4-OH-MET, 5-MeO-AMT, and 5-MeO-MiPT at monoamine receptors and transporters compared with the classic hallucinogens lysergic acid diethylamide (LSD ...
Hoener, Marius C.   +3 more
core   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

Correlation between blood and oral fluid psychoactive drug concentrations and cognitive impairment in driving under the influence of drugs [PDF]

open access: yes, 2017
The effects of drugs on driving performance should be checked with drug concentration in the brain and at the same time with the evaluation of both the behavioural and neurophysiological effects. The best accessible indicator of this information is the
Busardò, Francesco Paolo   +6 more
core   +1 more source

Small molecules as arthropod kinin receptor antagonists, feeding modulators, or novel mosquitocidal agents

open access: yesPest Management Science, EarlyView.
A two‐pronged screen of small molecules – (1) on recombinant kinin receptor and (2) through topical application – identifies kinin receptor antagonists, feeding behavior modulators, and new mosquitocidal molecules. Abstract BACKGROUND Aedes aegypti and Culex quinquefasciatus mosquitoes are primary vectors for numerous human and animal pathogens and ...
Bianca M. Henriques‐Santos   +1 more
wiley   +1 more source

Substance use in the club scene of Rome : a pilot study [PDF]

open access: yes, 2014
Date of Acceptance: 28/08/2014 Copyright © 2014 Alessandro Emiliano Vento et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium ...
Acciavatti, Tiziano   +11 more
core   +4 more sources

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

Neuropharmacology of new psychoactive substances (NPS): focus on the rewarding and reinforcing properties of cannabimimetics and amphetamine-like stimulants

open access: yesFrontiers in Neuroscience, 2016
New psychoactive substances (NPS) are a heterogeneous and rapidly evolving class of molecules available on the global illicit drug market (e.g smart shops, internet, dark net) as a substitute for controlled substances.
Cristina eMiliano   +5 more
doaj   +1 more source

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