Results 161 to 170 of about 37,355 (288)

BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells

Advanced Science, EarlyView.
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li, Nana Zhang, Zexin Bian, Baobao Geng, Liyun Cao, Peipei Liu, Zengming Li, Yan Zhao, Jun Tan   +8 more
wiley   +1 more source

Histopathological study of effects phenobarbital in Goats

, 2019
In this data was done to demonstrate the administration of phenobarbital compounds & showed histopathological effects. In this study fourteen of local goats were divided into two groups (each group seven animals) for 60 days.
Ali, Hanan, Al-zahra, Samera Abd, K, Zainab W.   +2 more
core  

Response: Rethinking GABAergic therapy in neonatal seizures: Beyond Scylla and Charybdis. [PDF]

Epilepsia Open
Thompson KW, Suchomelova L, Wasterlain CG.   +2 more
europepmc   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

Advanced Science, EarlyView.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun, Teng Ma, Hao Jin, Zelong Li, Yi Cheng, Jingjin Li, Lai‐Yu Kwok, Zhihong Sun   +7 more
wiley   +1 more source

Phototherapy Alone or Combined with Adjuvant Drugs for Neonatal Hyperbilirubinemia: A Systematic Review and Network Meta-Analysis. [PDF]

Children (Basel)
Fei Q, Liu H, Wang X, Yuan T.
europepmc   +1 more source

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

Advanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang, Yujing Shi, Zehua Gao, Jing Wang, Changsheng Liu   +4 more
wiley   +1 more source

Phenobarbital pharmacological findings on the nerve-muscle basis

, 2009
Phenobarbital and carbamazepine are antiepileptic drugs that act at the nervous central system by different mechanisms of action. In this work we investigated the pharmacological effects of these drugs on mouse phrenic nerve-diaphragm preparations ...
Barcelos, Caroline C., Costa Varca, Gustavo H., Andréo Filho, Newton, Barberato Fihlo, Silvio, Oshima-Franco, Yoko, Vila, Marta M. D. C., Rubem-Mauro, Leandro, Rocha Jr, Dimas S.   +7 more
core  

From Childhood Icterus to Adolescent Gallstones: Clinically Diagnosed Crigler-Najjar Syndrome Type II. [PDF]

Clin Case Rep
Goswami DK, Goswami B, Shaikh S, Rahimoon AG, Soni R, Kamil KA.   +5 more
europepmc   +1 more source

Designing Tissue Function Through Embedded Bioprinting Architectures

Advanced Science, EarlyView.
Embedded bioprinting enables soft, cell‐dense constructs to be fabricated within supporting bath environments. This review introduces a function‐guided framework linking target tissue functions to architectural requirements, supporting bath selection, bioink design, printing dynamics, and validation assays.
Qi Li, Yifei Cao, Jiaxin Lin, Huayong Yang, Hongzhao Zhou   +4 more
wiley   +1 more source

Lithium Toxicity or Alcohol Withdrawal? [PDF]

Cureus
Nagpal T, Baker T, Farooqui AS.
europepmc   +1 more source