Results 181 to 190 of about 2,545,958 (345)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

HSP90 as an evolutionary capacitor drives adaptive eye size reduction via atonal. [PDF]

open access: yesNat Commun
Sayed R   +8 more
europepmc   +1 more source

Cytotoxic T cells: Lyt phenotype and blocking of killing activity by Lyt antisera [PDF]

open access: green, 1979
Eiichi Nakayama   +4 more
openalex   +1 more source

TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection

open access: yesNature, 2019
Francesca Alfei   +19 more
semanticscholar   +1 more source

A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications

open access: yesMolecular Oncology, EarlyView.
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker   +3 more
wiley   +1 more source

Towards stratification in osteoarthritis: a review of the scientific terminology used in published basic research. [PDF]

open access: yesBMC Rheumatol
Pattappa G   +19 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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