Results 221 to 230 of about 2,909,871 (334)

Data from CXCL12γ Promotes Metastatic Castration-Resistant Prostate Cancer by Inducing Cancer Stem Cell and Neuroendocrine Phenotypes

, 2023
Younghun Jung, Frank C. Cackowski, Kenji Yumoto, Ann M. Decker, Jingcheng Wang, Jin Koo Kim, Eunsohl Lee, Yugang Wang, Jae‐Seung Chung, Amy Gursky, Paul H. Krebsbach, Kenneth J. Pienta, Todd M. Morgan, Russell S. Taichman   +13 more
openalex   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Integration of proxy intermediate omics traits into a nonlinear two-step model for accurate phenotypic prediction. [PDF]

Theor Appl Genet
Yoshioka H, Mary-Huard T, Aubert J, Toda Y, Ohmori Y, Yamasaki Y, Tsujimoto H, Takahashi H, Nakazono M, Takanashi H, Fujiwara T, Tsuda M, Kaga A, Inaba J, Fuji Y, Hirai MY, Nose Y, Kumaishi K, Usui E, Kobori S, Sato T, Narukawa M, Ichihashi Y, Iwata H.   +23 more
europepmc   +1 more source

Data from Coactivation of Estrogen Receptor and IKKβ Induces a Dormant Metastatic Phenotype in ER-Positive Breast Cancer

, 2023
Lamiaa El-Shennawy, Oleksii Dubrovskyi, Irida Kastrati, Jeanne M. Danes, Yiqun Zhang, Herbert E. Whiteley, Chad J. Creighton, Jonna Frasor   +7 more
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Uremic Toxin-Driven Vascular Calcification in Chronic Kidney Disease: Molecular Pathways and Integrated Phenotypes. [PDF]

Toxins (Basel)
Rivera RF, Sciarrone Alibrandi MT, Foligno NE, Magagnoli L, Ciceri P, Cozzolino M.   +5 more
europepmc   +1 more source

Data from Human Thyroid Tumor Cell Lines Derived from Different Tumor Types Present a Common Dedifferentiated Phenotype

, 2023
Wilma C.G. van Staveren, David Weiss Solís, Laurent Delys, Laurence Duprez, Guy Andry, Brigitte Franc, Gerry Thomas, Frédérick Libert, Jacques E. Dumont, Vincent Detours, Carine Maenhaut   +10 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A spectral component approach leveraging identity-by-descent graphs to address recent population structure in genomic analysis. [PDF]

Genome Res
Shemirani R, Belbin GM, Cullina S, Caggiano C, Gignoux CR, Zaitlen N, Kenny EE.   +6 more
europepmc   +1 more source

Supplementary Methods and Materials from Identification of Griseofulvin as an Inhibitor of Centrosomal Clustering in a Phenotype-Based Screen

, 2023
Blanka Rebacz, Thomas Ostenfeld Larsen, Mads H. Clausen, Mads H. Rønnest, H. Löffler, Anthony D. Ho, Alwin Krämer   +6 more
openalex   +1 more source