Results 241 to 250 of about 3,800,975 (380)

Phenotype [PDF]

, 2019
Mukesh Meena, Prashant Swapnil, Tansukh Barupal, Kuldeep Sharma, Tripta Jain   +4 more
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Health interoperability across phenotypes of family physician practices. [PDF]

J Am Med Inform Assoc
Everson J, Strawley C.
europepmc   +1 more source

Characteristics of Pruritus according to Morphological Phenotype of Psoriasis and Association with Neuropeptides and Interleukin-31 [PDF]

, 2020
Sung‐Min Park, Gun‐Wook Kim, Hoon‐Soo Kim, Hyun‐Chang Ko, Moon‐Bum Kim, Byung‐Soo Kim   +5 more
openalex   +1 more source

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma.

Cancer Cell, 2010
H. Noushmehr, D. Weisenberger, K. Diefes, H. Phillips, Kanan D. Pujara, B. Berman, F. Pan, C. Pelloski, E. Sulman, K. Bhat, R. Verhaak, K. Hoadley, D. Hayes, C. Perou, Heather K. Schmidt, L. Ding, R. Wilson, D. J. Van Den Berg, Hui Shen, H. Bengtsson, P. Neuvial, L. Cope, J. Buckley, J. Herman, S. Baylin, P. Laird, K. Aldape   +26 more
semanticscholar   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

DINO-EYE: self-supervised learning for identification of different optic disc phenotypes in primary open angle glaucoma. [PDF]

Sci Rep
Grassi L, Fei Z, Morales E, Caprioli J.
europepmc   +1 more source

Nicotine Replacement, Topography, and Smoking Phenotypes of E-cigarettes

, 2016
Andrew A. Strasser, Valentina Souprountchouk, Amanda Kaufmann, Sonja Blazekovic, Frank T. Leone, Neal L. Benowitz, Robert A. Schnoll   +6 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Mechanisms Linking Insomnia and Cardiometabolic Disease Risk. [PDF]

Arterioscler Thromb Vasc Biol
Fernandez-Mendoza J.
europepmc   +1 more source