Results 311 to 320 of about 3,800,975 (380)

Beyond the diagnosis: Unraveling <i>DSPP</i> genotype-phenotype correlations in dentin dysplasia and dentinogenesis imperfecta. [PDF]

Jpn Dent Sci Rev
Boonyakanog A, Sriwangyang K, Eamtanaporn T, Krasaesin A, Fakhruddin KS, Chantarangsu S, Cho SD, Rokny HA, Porntaveetus T.   +8 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Prevalence and incidence of amyloid transthyretin amyloidosis in the USA: insights from claims databases and electronic health records. [PDF]

Open Heart
Laires PA, Li X, Uday AM, Quarta CC, Silva AM.   +4 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Iron, Oxidative Stress, and Haptoglobin Gene Polymorphism in Sickle Cell Disease Patients With Inflammation in Cameroon: An Analytical Cross-Sectional Study. [PDF]

Biochem Res Int
Tuono De Manfouo R, Simo Louokdom J, Chedjou JP, Biapa Nya PC, Mbatcham W, Tayou Tagny C, Pieme CA.   +6 more
europepmc   +1 more source

Relationship between OSA pathophysiological phenotypes and treatment response to mandibular advancement devices: a pilot study [PDF]

Izabella Paola Manetta, Bruno Duarte, Luciana Bertoldi Nucci, Carla Cristina Enes   +3 more
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Subphenotyping sepsis based on organ interaction trajectory using a deep temporal graph clustering model: a retrospective cohort study. [PDF]

EClinicalMedicine
Feng X, Sun L, Zhu J, Yao X, Zhang Z, Pan Q, Fang L, Ning G.   +7 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Clinical Phenotypes of Obstructive Sleep Apnea: A Decade of Evidence Toward Personalized Management. [PDF]

Pathophysiology
Rosales W, Vanka SC, Singh H, Bhamrah P, Bhamrah M, Ghildiyal N, Liendo C, Asghar S, Alexander JS, Chernyshev OY.   +9 more
europepmc   +1 more source