An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang +10 more
wiley +1 more source
Beyond Resistance: Phenotypic Plasticity in Bacterial Responses to Antibiotics, Oxidative Stress and Antimicrobial Photodynamic Inactivation. [PDF]
Rapacka-Zdonczyk A.
europepmc +1 more source
This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao +13 more
wiley +1 more source
BRCA1: An Unrecognized Modulator of Lineage Plasticity in Basal-like Breast Cancer. [PDF]
Sanawar R, Sengodan SK.
europepmc +1 more source
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Decoding the Molecular Drivers of Epithelial to Mesenchymal Transition in Breast Cancer: Insights into Epithelial Plasticity and Microenvironment Crosstalk. [PDF]
Peri E +5 more
europepmc +1 more source
Early-life stasis in partial seasonal migration is underpinned by among-cohort variation in migratory plasticity and selective disappearance. [PDF]
Ugland CR +13 more
europepmc +1 more source
"Brake" and "accelerator": revisiting tumor cell direct responses and the paradox of aggression in anti-VEGF therapy. [PDF]
Wei P +5 more
europepmc +1 more source
Unveiling the Genomic Architecture of Phenotypic Plasticity Using Multiple GWAS Approaches Under Contrasting Conditions of Water Availability: A Model for Barley. [PDF]
Arenas S, Cortés AJ.
europepmc +1 more source

