Results 181 to 190 of about 61,326 (219)
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The Journal of Allergy and Clinical Immunology: In Practice, 2020
Rhinitis is an umbrella term of a group of upper airway diseases with nasal symptoms and signs with different etiologies and various clinical features or traits. It can be classified into different "phenotypes," based on these observable traits. A proper differential diagnosis is necessary to adequately manage the disease.
Joaquim, Mullol +2 more
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Rhinitis is an umbrella term of a group of upper airway diseases with nasal symptoms and signs with different etiologies and various clinical features or traits. It can be classified into different "phenotypes," based on these observable traits. A proper differential diagnosis is necessary to adequately manage the disease.
Joaquim, Mullol +2 more
openaire +2 more sources
Methods, 2011
Model organisms like the mouse are important tools to learn more about gene function in man. Within the last 20 years many mutant mouse lines have been generated by different methods such as ENU mutagenesis, constitutive and conditional knock-out approaches, knock-down, introduction of human genes, and knock-in techniques, thus creating models which ...
Helmut, Fuchs +49 more
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Model organisms like the mouse are important tools to learn more about gene function in man. Within the last 20 years many mutant mouse lines have been generated by different methods such as ENU mutagenesis, constitutive and conditional knock-out approaches, knock-down, introduction of human genes, and knock-in techniques, thus creating models which ...
Helmut, Fuchs +49 more
openaire +2 more sources
Respiratory Care, 2023
COPD is a heterogeneous condition, the onset and trajectory of which is influenced not only by tobacco exposure but also an individual's genetics and the exposures they accumulate over their life course. In such a complex chronic disease, phenotyping individuals based on similar clinical or molecular characteristics can aid in guiding appropriate ...
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COPD is a heterogeneous condition, the onset and trajectory of which is influenced not only by tobacco exposure but also an individual's genetics and the exposures they accumulate over their life course. In such a complex chronic disease, phenotyping individuals based on similar clinical or molecular characteristics can aid in guiding appropriate ...
openaire +2 more sources
Journal of Mathematical Biology, 2009
The topological viewpoint on spaces of phenotypes presented in Stadler et al. (J Theor Biol 213:241-274, 2001) is revisited, and a quantified version is proposed. While necessary probabilistic information can be encoded in a topological- like fashion, it turns out that it is not reflected adequately by the concept of continuity.
Mynard, Frédéric D. +1 more
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The topological viewpoint on spaces of phenotypes presented in Stadler et al. (J Theor Biol 213:241-274, 2001) is revisited, and a quantified version is proposed. While necessary probabilistic information can be encoded in a topological- like fashion, it turns out that it is not reflected adequately by the concept of continuity.
Mynard, Frédéric D. +1 more
openaire +4 more sources
Nature Biotechnology, 2015
In the coming years, patient phenotypes captured to enhance health and wellness will extend to human interactions with digital technology.
Sachin H, Jain +3 more
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In the coming years, patient phenotypes captured to enhance health and wellness will extend to human interactions with digital technology.
Sachin H, Jain +3 more
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Electrophoresis, 1999
Within the framework of a pilot project on the analysis of the mouse proteome, we investigated C57BL/6 mice (Mus musculus), a standard inbred strain of the mouse, starting with the analysis of brain, liver and heart proteins. Tissue extraction and the separation of proteins were performed with techniques offering a maximum of resolution.
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Within the framework of a pilot project on the analysis of the mouse proteome, we investigated C57BL/6 mice (Mus musculus), a standard inbred strain of the mouse, starting with the analysis of brain, liver and heart proteins. Tissue extraction and the separation of proteins were performed with techniques offering a maximum of resolution.
openaire +2 more sources
Current Opinion in Pulmonary Medicine, 2019
Bronchiectasis is a chronic respiratory disease with heterogeneous clinical manifestations and outcomes. Identifying clinical phenotypes could help in managing bronchiectasis patients and hopefully improve disease prognosis by adopting personalized treatment. We review the current literature on clinical phenotypes of bronchiectasis and try to highlight
Patricia, Chang-Macchiu +2 more
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Bronchiectasis is a chronic respiratory disease with heterogeneous clinical manifestations and outcomes. Identifying clinical phenotypes could help in managing bronchiectasis patients and hopefully improve disease prognosis by adopting personalized treatment. We review the current literature on clinical phenotypes of bronchiectasis and try to highlight
Patricia, Chang-Macchiu +2 more
openaire +2 more sources
IEEE Software, 2003
Is it a requirement or a solution? Is it at the right level of detail? The author has come up with an elegant way of addressing these questions by using a metaphor drawn from the genetics field. Try applying the idea to your project and write and tell us the results.
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Is it a requirement or a solution? Is it at the right level of detail? The author has come up with an elegant way of addressing these questions by using a metaphor drawn from the genetics field. Try applying the idea to your project and write and tell us the results.
openaire +1 more source
Consciousness and Cognition, 2011
Self-awareness is viewed here as the phenotypic expression of an interaction between genes and the environment. Brain and behavioral development of fetuses and newborn infants are a rich source of information regarding what might constitute minimal self-awareness. Research indicates that newborns have feeling (subjective) experience.
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Self-awareness is viewed here as the phenotypic expression of an interaction between genes and the environment. Brain and behavioral development of fetuses and newborn infants are a rich source of information regarding what might constitute minimal self-awareness. Research indicates that newborns have feeling (subjective) experience.
openaire +2 more sources