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Epimutations and mutations, nurturing phenotypic diversity
Genetica, 2021Epimutations and mutations are two dissimilar mechanisms that have contributed to the phenotypic diversities in organisms. Though dissimilar, many previous studies have revealed that the consequences of epimutations and mutations are not mutually exclusive. DNA rich in epigenetic modifications can be prone to mutations and vice versa. In order to get a
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Diversity and evolution of actin-dependent phenotypes
Current Opinion in Genetics & Development, 2019The actin cytoskeleton governs a vast array of core eukaryotic phenotypes that include cell movement, endocytosis, vesicular trafficking, and cytokinesis. Although the basic principle underlying these processes is strikingly simple - actin monomers polymerize into filaments that can depolymerize back into monomers - eukaryotic cells have sophisticated ...
Katrina B, Velle +1 more
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On the Influence of Phenotype Plasticity on Genotype Diversity
2007 IEEE Symposium on Foundations of Computational Intelligence, 2007A large body of research has investigated the advantages of combining phenotype adaptation and genotype adaptation. The hybridization of genetic search and local search methods, often known as memetic algorithms, and the influence of learning on evolution, i.e., the Baldwin effect and the hiding effect, have been widely studied.
Ingo Paenke, Jürgen Branke, Yaochu Jin
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Diversity of the osteoblastic phenotype.
Ciba Foundation symposium, 1989Studies of bone cells in culture have raised two salient questions: are the findings representative of the in vivo situation and can the conflicting data from different cell models be reconciled? Review of the literature indicates that all osteoblastic cells, defined by their origin or by their ability to produce mineralized matrix, have a few common ...
G A, Rodan +4 more
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Experimental approaches to phenotypic diversity in infection
Current Opinion in Microbiology, 2015Microbial infections are burdening human health, even after the advent of antibiotics, vaccines and hygiene. Thus, infection biology has aimed at the molecular understanding of the pathogen-host interaction. This has revealed key virulence factors, host cell signaling pathways and immune responses. However, our understanding of the infection process is
Kreibich Saskia, Hardt Wolf-Dietrich
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Phenotypic diversity in leukemia cell populations
CANCER AND METASTASIS REVIEW, 1983Acute leukemia comprises a large group of different diseases that can be identified by morphology in combination with immunological markers. Such studies suggest that phenotypic heterogeneity may be expressed in individual leukemia cell populations.
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Promoting Phenotypic Diversity in Genetic Programming
2010Population diversity is generally seen as playing a crucial role in the ability of evolutionary computation techniques to discover solutions. In genetic programming, diversity metrics are usually based on structural properties of individual program trees, but are also sometimes based on the spread of fitness values in the population. We explore the use
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Study on the Phenotypic Diversity of 33 Ornamental Xanthoceras sorbifolium Cultivars
Plants, 2023Fuliang Cao +2 more
exaly
The Wilson's disease gene and phenotypic diversity
Journal of Hepatology, 2001S M, Riordan, R, Williams
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