Results 131 to 140 of about 281,706 (265)

Rhizosphere microbial patterns and climatic correlates of phenotypic variation in <i>Rosa roxburghii</i>. [PDF]

Front Microbiol
Qin H, Gong H, Wang X, Liu Y, Song W, Li Z, Xiang H.   +6 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Genomic structure, phenotypic variation and drivers of diversification in <i>Euphonia hirundinacea</i> (Aves: Fringilidae). [PDF]

PeerJ
Vázquez-López M, Zamudio-Beltrán LE, Ramírez-Barrera SM, Escalante-Pliego P, Hernández-Baños BE.   +4 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Uncovering Phenotypic Variation in Common Bean (<i>Phaseolus vulgaris</i> L.): Insights from the INCREASE Project. [PDF]

Plants (Basel)
Hasanaklou HT, Sinkovič L, Papa R, Bitocchi E, Bellucci E, Dolničar P, Pipan B.   +6 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Methylome differences among barley inbreds and their association with genomic, transcriptomic, and phenotypic variation. [PDF]

J Exp Bot
Kühl M, Wu PY, Shrestha A, Engelhorn J, Mukherjee S, Hartwig T, Stich B.   +6 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

A comparison of interspecific and intraspecific phenotypic variation in spectral signatures of ferns with robust versus uncertain species boundaries. [PDF]

J Plant Res
Mendonça NA, de Oliveira MHV, Almeida TE.   +2 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source