Sigma-E is required for the production of the antibiotic actinomycin in Streptomyces antibioticus
, 1997 The phsA gene encodes phenoxazinone synthase (PHS), which catalyses the penultimate step in the pathway for actinomycin biosynthesis in Streptomyces antibioticus.
Leony Chamberlin +7 more
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Phenoxazinone Synthase-like Activity of Rationally Designed Heme Enzymes Based on Myoglobin
The design of functional metalloenzymes is attractive for the biosynthesis of biologically important compounds, such as phenoxazinones and phenazines catalyzed by native phenoxazinone synthase (PHS).
Jia-Jia Lang (5472917) +7 more
core +1 more source
The Trypanosoma brucei sphingolipid synthase, an essential enzyme and a drug target [PDF]
, 2009 Sphingolipids are important structural components of eukaryotic membranes, in addition they and their precursors are involved in signal transduction processes.
Pan, Ssu-Ying
core
Uncovering the Cryptic Gene Cluster ahb for 3-amino-4-hydroxybenzoate Derived Ahbamycins, by Searching SARP Regulator Encoding Genes in the Streptomyces argillaceus Genome. [PDF]
Int J Mol Sci, 2023 Ye S +10 more
europepmc +1 more source
Potential of the enzyme laccase for the synthesis and derivatization of antimicrobial compounds. [PDF]
World J Microbiol Biotechnol, 2023 Hahn V.
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Recent developments in the identification and biosynthesis of antitumor drugs derived from microorganisms. [PDF]
Eng Microbiol, 2022 Gao Q, Deng S, Jiang T.
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, 1992 Phenoxazinone synthase (PHS) catalyzes the penultimate step in the actinomycin D biosynthetic pathway of Streptomyces antibioticus. Earlier, a 4.3 kb DNA sequence derived from S.
Fawaz, Farah Said
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A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties. [PDF]
Front Chem, 2021 Balewski Ł +3 more
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Copper(ii) and silver(i) complexes with dimethyl 6-(pyrazine-2-yl)pyridine-3,4-dicarboxylate (py-2pz): the influence of the metal ion on the antimicrobial potential of the complex. [PDF]
RSC Adv, 2023 Andrejević TP +9 more
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Isolation, characterization, anti-MRSA evaluation, and in-silico multi-target anti-microbial validations of actinomycin X2 and actinomycin D produced by novel Streptomyces smyrnaeus UKAQ_23. [PDF]
Sci Rep, 2021 Qureshi KA +15 more
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