Results 111 to 120 of about 1,180 (161)

Gut metabolome and microbiota signatures predict response to treatment with exclusive enteral nutrition in a prospective study in children with active Crohn's disease. [PDF]

Am J Clin Nutr
Nichols B, Briola A, Logan M, Havlik J, Mascellani A, Gkikas K, Milling S, Ijaz UZ, Quince C, Svolos V, Russell RK, Hansen R, Gerasimidis K.   +12 more
europepmc   +1 more source

Advances in the Synthesis and Biological Applications of Enoxacin-Based Compounds. [PDF]

Biomolecules
Suleiman G, El Brahmi N, Guillaumet G, El Kazzouli S.   +3 more
europepmc   +1 more source

Nur77 protects the bladder urothelium from intracellular bacterial infection. [PDF]

Nat Commun
Collins CA, Waller C, Batourina E, Kumar L, Mendelsohn CL, Gilbert NM.   +5 more
europepmc   +1 more source

Component characterization of <i>Smilax glabra</i> Roxb., and its inhibitory activity against <i>Helicobacter pylori</i> through targeted suppression of its secreted urease. [PDF]

Front Cell Infect Microbiol
Tang Y, Yang F, Wen X, Zhou Y, Tang R, He X, Lu Q, Li C.   +7 more
europepmc   +1 more source

Disubstituted Meldrum's Acid: Another Scaffold with SuFEx-like Reactivity. [PDF]

Molecules
Chen B, Wang Z, Peng X, Xie J, Sun Z, Li L.   +5 more
europepmc   +1 more source

Bioproduction of Natural Phenethyl Acetate, Phenylacetic Acid, Ethyl Phenylacetate, and Phenethyl Phenylacetate from Renewable Feedstock

ChemSusChem, 2022
AbstractNatural phenethyl acetate (PEA), phenylacetic acid (PAA), ethyl phenylacetate (Et‐PA), and phenethyl phenylacetate (PE‐PA) are highly desirable aroma chemicals, but with limited availability and high price. Here, green, sustainable, and efficient bioproduction of these chemicals as natural products from renewable feedstocks was developed.
Balaji Sundara Sekar, Xirui Li, Zhi Li
openaire   +2 more sources

Ornithine phenylacetate revisited

Metabolic Brain Disease, 2013
In patients with liver failure hyperammonemia is associated with the development of hepatic encephalopathy (HE) and immune impairment. Treatment of hyperammonemia is an unmet clinical need. Ornithine phenylacetate (OP) is a novel drug that is targeted at reducing ammonia concentration in patients with liver disease and therefore a potential treatment ...
Maria, Jover-Cobos, Lorette, Noiret, Yalda, Sharifi, Rajiv, Jalan   +3 more
openaire   +2 more sources

Phenylacetic acid excretion in man

Analytical Biochemistry, 1979
A rapid, reliable, sensitive, and highly specific mass fragmentographic method for the quantification of phenylacetic acid (PAA) in urine is described. The method was used to determine total, conjugated, and free PAA simultaneously in normal urine. The mean ± SE excretion of total, conjugated, and free PAA in urine of 24 normal adult volunteers were ...
M E, Martin, F, Karoum, R J, Wyatt
openaire   +2 more sources

VULNERABILITY OF THE IMMATURE BRAIN TO PHENYLACETATE INTOXICATION: TISSUE PERMEABILITY TO PHENYLACETATE

Journal of Neurochemistry, 1979
AbstractIn the rat phenylacetate readily penetrates into such tissues as brain, eyes, heart, kidneys, and liver. One hour after the subcutaneous injection of sodium phenylacetate into rats ranging in age from 1 to 65 days, the ratios of the concentrations (μmolig) in blood/tissue were approx 1:1 in all of these tissues with the exception of the brain ...
Y H, Loo, T, Fulton, H M, Wisniewski
openaire   +2 more sources

Dissociation constants of phenylacetic acid and three substituted phenylacetic acids

Journal of the Chemical Society B: Physical Organic, 1971
The dissociation constants of four acids in aqueous solution have been determined at 25° by means of conductivity measurements. The pK values are: phenylacetic acid, 4·310; o-methylphenylacetic acid, 4·297; o-ethylphenylacetic acid, 4·317; o-fluorophenylacetic acid, 4·093.
Wayne C. Duer, R. A. Robinson
openaire   +1 more source