Results 1 to 10 of about 320,811 (207)

Aminopeptidase C of Aspergillus niger is a Novel Phenylalanine Aminopeptidase [PDF]

, 2003
A novel enzyme with a specific phenylalanine aminopeptidase activity (ApsC) from Aspergillus niger (CBS 120.49) has been characterized. The derived amino acid sequence is not similar to any previously characterized aminopeptidase sequence but does share ...
Basten, E.J.W., Dekker, P.J.T., Schaap, P.J.   +2 more
core   +13 more sources

Combining metabolite doping and metabolic engineering to improve 2-phenylethanol production by engineered cyanobacteria

Frontiers in Bioengineering and Biotechnology, 2022
2-Phenylethanol (2-PE) is a rose-scented aromatic compound, with broad application in cosmetic, pharmaceutical, food and beverage industries. Many plants naturally synthesize 2-PE via Shikimate Pathway, but its extraction is expensive and low-yielding ...
Giulia Usai, Giulia Usai, Alessandro Cordara, Angela Re, Maria Francesca Polli, Maria Francesca Polli, Giuseppe Mannino, Cinzia Margherita Bertea, Debora Fino, Candido Fabrizio Pirri, Candido Fabrizio Pirri, Barbara Menin   +11 more
doaj   +1 more source

High phenylalanine concentrations induce demyelination and microglial activation in mouse cerebellar organotypic slices

Frontiers in Neuroscience, 2022
Phenylketonuria (PKU) is an inborn error of metabolism. Mutations in the enzyme phenylalanine hydroxylase (PAH)-encoding gene lead to a decreased metabolism of the amino acid phenylalanine (Phe).
Orli Thau-Zuchman, Patrick N. Pallier, Paul J. M. Savelkoul, Almar A. M. Kuipers, J. Martin Verkuyl, Adina T. Michael-Titus   +5 more
doaj   +1 more source

QUANTITATIVE COMPOSITION OF ESSENTIAL L-AMINO ACIDS IN BLENDED THERAPEUTIC DIETARY PRODUCTS FOR PEOPLE WITH PHENYLKETONURIA

Вісник проблем біології і медицини, 2022
Phenylketonuria is one of the most common genetic diseases among the European population that manifests by increased blood phenylalanine content. It has been proven that diet therapy by restricting or excluding phenylalanine is vital for this group of ...
Kolinko L. M., Mishchenko I. V., Kokovskaya O. V.   +2 more
doaj   +1 more source

Amino acid δ15N underestimation of cetacean trophic positions highlights limited understanding of isotopic fractionation in higher marine consumers

Ecology and Evolution, 2020
Compound‐specific stable isotope analysis (CSIA) of amino acids (AAs) has been rapidly incorporated in ecological studies to resolve consumer trophic position (TP).
Cory J. D. Matthews, Rocio I. Ruiz‐Cooley, Corinne Pomerleau, Steven H. Ferguson   +3 more
doaj   +1 more source

Prospects for Cell-Directed Curative Therapy of Phenylketonuria (PKU) [PDF]

Molecular Frontiers Journal, 2019
Phenylketonuria (PKU) due to recessively inherited phenylalanine hydroxylase (PAH) deficiency is among the most common inborn errors of metabolism. Dietary therapy begun early in infancy prevents the major manifestations of the disease but shortcomings ...
Cary O. Harding
doaj   +1 more source

Polypeptide gels incorporating the exotic functional aromatic amino acid 4-amino-L-phenylalanine [PDF]

, 2018
High-molecular-weight polypeptides with functional aromatic side chains, poly(4-amino-l-phenylalanine), were prepared by the metal-initiated polymerization of the Nα-carboxyanhydride of the corresponding amino acid, which is a microbial derivative of ...
Ali, Mohammad Asif, Captain, Ilya, Deming, Timothy J, Kaneko, Tatsuo, Perlin, Pesach   +4 more
core   +1 more source

Distinct Metabolites for Photoreactive l-Phenylalanine Derivatives in Klebsiella sp. CK6 Isolated from Rhizosphere of a Wild Dipterocarp Sapling

Molecules, 2013
Photoaffinity labeling is a reliable analytical method for biological functional analysis. Three major photophores—aryl azide, benzophenone and trifluoromethyldiazirine—are utilized in analysis.
Yasumaru Hatanaka, Yasuyuki Hashidoko, Irnayuli R. Sitepu, Yasuko Sakihama, Dongyeop Kim, Reika Isoda, Takashi Murotani, Masashi Okamoto, Haruka Ikemoto, Yasuyuki Muto, Munenori Sakurai, Yuta Murai, Wataru Hisano, Lei Wang, Makoto Hashimoto   +14 more
doaj   +1 more source

Phenylalanine promotes alveolar macrophage pyroptosis via the activation of CaSR in ARDS

Frontiers in Immunology, 2023
Acute respiratory distress syndrome (ARDS) is associated with high mortality rates in patients admitted to the intensive care unit (ICU) patients with overwhelming inflammation considered to be an internal cause.
Yiding Tang, Yue Yu, Ranran Li, Zheying Tao, Li Zhang, Xiaoli Wang, Xiaoling Qi, Yinjiaozhi Li, Tianjiao Meng, Hongping Qu, Mi Zhou, Jing Xu, Jialin Liu   +12 more
doaj   +1 more source

Three protected tetrapeptides [PDF]

, 1996
The structures of three protected tetrapeptides, containing the Boc-Gly-Gly-Phe-X-OMe chain, tert-butoxycarbonyl-glycy-glycl-phenylalanine-leucine methyl ester dihydrate, Boc-Gly-Gly-L-Phe-D-Leu-OMe, C25H38N4O7·2H2O, tert-butoxycarbonyl-glycy-glycl ...
Casalone, Gianluigi, Fenude, Emma
core   +1 more source