Results 221 to 230 of about 394,077 (382)

Editorial: Immunosuppressive Amino Acid Catabolizing Enzymes in Heallth and Disease

open access: yesFrontiers in Immunology, 2021
Flavia Castellano   +4 more
doaj   +1 more source

Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering.

open access: yesJournal of the American Chemical Society, 2016
S. Meisburger   +5 more
semanticscholar   +1 more source

N‐Amino Peptide–Graphene Quantum Dot Loaded Small Extracellular Vesicles for Targeted Therapy of Tauopathies

open access: yesAdvanced NanoBiomed Research, EarlyView.
A neuron‐targeting drug delivery system is developed by incorporating the tau‐specific N‐amino peptide, mxyl‐NAP2, with graphene quantum dots (GQDs) and encapsulating the complex into small extracellular vesicles functionalized with a neuron‐targeting ligand.
Runyao Zhu   +5 more
wiley   +1 more source

Crown Ether–Peptide Rotaxanes

open access: yesAngewandte Chemie, EarlyView.
The synthesis of crown ether‐peptide rotaxanes is reported, incorporating a broad range of canonical and unnatural peptides into a threaded peptide backbone without the need for additional nonamide template sites in the axle. The 24C8 macrocycle is locked on the glycine residue used to assemble the rotaxane, allowing the formation of different ...
Peng‐Lai Wang   +9 more
wiley   +2 more sources

Mechanochemische Methoden mit Anwendung in der Late‐Stage Modifizierung Pharmazeutisch Wirksamer Verbindungen

open access: yesAngewandte Chemie, EarlyView.
Dieser Review diskutiert mechanochemische Strategien zur späten Modifizierung bioaktiver Wirkstoffe und bietet zugleich eine wertvolle Übersicht zur Auswahl geeigneter Substrate, um das pharmazeutische Potenzial neuer und bestehender (mechano)chemischer Verfahren zu evaluieren.
Johanna Templ, Lars Borchardt
wiley   +1 more source

Bispecific DNA‐Peptide Probes for Targeting Receptor Pairs on Live Cells

open access: yesAngewandte Chemie, EarlyView.
DNA duplex‐programmed presentation of two different (cyclo)peptides provides bispecific agents that recognize unique fingerprints of cells through improved avidity and specificity. Bispecific DNA‐cyclopeptide complexes enabled a cell‐specific targeting and internalization of cytotoxic payload.
Pritam Ghosh   +6 more
wiley   +2 more sources

The influence of menstrual cycle on metabolic control and diet in patients with phenylketonuria. [PDF]

open access: yesOrphanet J Rare Dis
Horka L   +6 more
europepmc   +1 more source

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