Results 221 to 230 of about 155,562 (237)
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Photophysics of phenylalanine analogues
Journal of Photochemistry and Photobiology A: Chemistry, 2001The photophysical properties (fluorescence quantum yields and lifetimes) of linear analogues of phenylalanine (Phe) [β-homophenylalanine (β-Hph), β-phenylalanine (β-Phe), phenyglycine (Phg)] in water at pH=6 and 1 have been measured. The obtained results indicate that relative space location of the amino, carboxyl groups and phenyl chromophore ...
Joanna Malicka +5 more
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Inhibition of dihydroxyphenylalanine decarboxylase by derivatives of phenylalanine
Archives of Biochemistry and Biophysics, 1954Abstract A series of compounds, related chemically to phenylalanine, have been examined for their action on dopa decarboxylase of pig kidney and on bacterial tyrosine decarboxylase. Some of the compounds were found to inhibit these enzymes. The relation between degree of inhibition and chemical structure of the inhibitors has been discussed ...
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Phenylketonuria: Phenylalanine Neurotoxicity
2015Phenylketonuria (PKU) was the first inherited metabolic disease identified by newborn screening and treated with diet to prevent the development of intellectual disability. Classification of the severity of phenylketonuria is based on the genetic mutation, dietary phenylalanine tolerance, and pretreatment blood phenylalanine concentrations ...
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Toxicology and Applied Pharmacology, 2000
Ochratoxin A (OTA) is a nephrotoxic, hepatotoxic, and teratogenic mycotoxin produced by storage molds on a variety of foodstuffs. Its chemical structure is composed of an isocumarin part linked to l-phenylalanine. Inhibition of phenylalanine hydroxylase and other enzymes that use phenylalanine as substrate is based on this structural homology.
Tihana Žanić-Grubišić +5 more
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Ochratoxin A (OTA) is a nephrotoxic, hepatotoxic, and teratogenic mycotoxin produced by storage molds on a variety of foodstuffs. Its chemical structure is composed of an isocumarin part linked to l-phenylalanine. Inhibition of phenylalanine hydroxylase and other enzymes that use phenylalanine as substrate is based on this structural homology.
Tihana Žanić-Grubišić +5 more
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Phenylalanine deficiency syndrome
The Journal of Pediatrics, 1966Clinical observations are recorded on two infants in whom failure to gain, eczema and listlessness developed during severe dietary restriction of phenylalanine. Regular diet was resumed when they were found not to have phenylketonuria; in spite of improvement in their nutritional status, their developmental progress remained slow.
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The availability of D-phenylalanine and DL-phenylalanine
American Journal of Psychiatry, 1985J G Lofft, R H Bridenbaugh
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The metabolism of phenylalanine.
1966The metabolism of phenylalanine-C14 was studied in three different groups of rats: normal animals, phenylalanine-deficient animals and rats which had been maintained on a high (5 and 7%) phenylalanine diet from 21 days of age and considered to be "experimentally phenylketonuric".
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Effects of phenylalanine on phenylalanine hydroxylase separation and stability
Biochemical Medicine, 1985Ennis C. Layne +2 more
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