Results 331 to 340 of about 425,330 (380)

Preparation and Taste Characteristics of Kokumi N-Lactoyl Phenylalanine in the Presence of Phenylalanine and Lactate.

Journal of Agricultural and Food Chemistry, 2022
N-l-Lactoyl phenylalanine (N-l-lactoyl-Phe) has been identified as a taste-active contributor in many fermented foods. However, its preparation, taste property, and content in foodstuffs are little known to date.
Jing Wu, Jingrong Gao, Junjie Lin, Chun Cui, Laihao Li, Shan He, Charles Brennan   +6 more
semanticscholar   +1 more source

Phenylalanine hydroxylase mutations and phenylalanine-tyrosine metabolism in heterozygotes for phenylalanine hydroxylase deficiency

Acta Paediatrica, 2002
The aim of this study was to determine whether any relationship exists between the severity of mutation of the phenylalanine hydroxylase (PAH) gene and the plasma concentrations of phenylalanine (Phe) and tyrosine (Tyr) under fasting and semifasting conditions among heterozygotes in a matched case-control study.
E. Verduci, E. Riva, C. Agostoni, S. Leviti, L. Fiori, A.M. Lammardo, M. L. Biondi, M. Giovannini   +7 more
openaire   +4 more sources

Phenylalanine supplementation improves the phenylalanine profile in tyrosinaemia

Journal of Inherited Metabolic Disease, 2000
AbstractTyrosinaemia types I and II are caused by enzyme deficiencies in the tyrosine catabolism pathway. Successful treatment is possible with the novel enzyme inhibitor NTBC in tyrosinaemia type I and with dietary tyrosine and phenylalanine restriction in both conditions.
C J, Wilson, K G, Van Wyk, J V, Leonard, P T, Clayton   +3 more
openaire   +2 more sources

Effects of tetrahydrobiopterin and phenylalanine on in vivo human phenylalanine hydroxylase by phenylalanine breath test

Molecular Genetics and Metabolism, 2007
BH(4) administration results in the reduction of blood phenylalanine level in patients with tetrahydrobiopterin (BH(4))-responsive phenylalanine hydroxylase (PAH) deficiency. The mechanism underlying BH(4) response remains unknown. Here, we studied the effects of BH(4) and phenylalanine on in vivo PAH activity of normal controls using the phenylalanine
Yoshiyuki, Okano, Kazuhiko, Takatori, Satoshi, Kudo, Tomoko, Sakaguchi, Minoru, Asada, Masahiro, Kajiwara, Tsunekazu, Yamano   +6 more
openaire   +2 more sources

Effect of dietary phenylalanine level on growth performance, body composition, and biochemical parameters in plasma of juvenile hybrid tilapia, Oreochromis niloticus × Oreochromis aureus

Journal of the World Aquaculture Society, 2020
An 8‐week feeding trial with juvenile hybrid tilapia (Oreochromis niloticus × Oreochromis aureus) was conducted to assess the effects of dietary phenylalanine on growth, body composition, and biochemical parameters in plasma.
Wei Xiao, Zhi‐Ying Zou, Dayu Li, Jinglin Zhu, Y. Yue, Hong Yang   +5 more
semanticscholar   +1 more source

Phenylalanine Induces Pulmonary Hypertension Through Calcium-Sensing Receptor Activation.

American Journal of Physiology - Lung cellular and Molecular Physiology, 2020
BACKGROUND Phenylalanine levels are associated with pulmonary hypertension in metabolic profiling clinical studies. However, the pathophysiologic role of phenylalanine on pulmonary circulation is still unclear.
Rubin Tan, Jian-sha Li, Fangbo Liu, P. Liao, M. Ruiz, J. Dupuis, Li-ping Zhu, Q. Hu   +7 more
semanticscholar   +1 more source

Activation of phenylalanine hydroxylase by phenylalanine

Biochimica et Biophysica Acta (BBA) - Enzymology, 1971
Abstract 1. 1. Phenylalanine activates phenylalanine hydroxylase ( l -phenylalanine, tetrahydropteridine:oxygen oxidoreductase (4-hydroxylating), EC 1.14.3.1), when dithiothreitol is used to regenerate 2-amino-4-hydroxy-6,7-dimethyltetrahydropteridine. 2. 2.
openaire   +2 more sources

Determination of p-halogenated phenylalanines and phenylalanine in plasma

Analytical Biochemistry, 1971
Abstract A method for the determination, either in combination or singularly, for phenylalanine or some p -halogenated phenylalanines in blood plasma is presented. A thin-layer chromatographic procedure was elaborated which separates the p -halogenated phenylalanines from phenylalanine by means of a cation-exchange resin.
openaire   +2 more sources

The use of deuterated phenylalanine for the elucidation of the phenylalanine-tyrosine metabolism

Clinica Chimica Acta, 1972
Abstract The application in vivo of stable isotopes, e.g. deuterium, for the study of metabolic pathways is demonstrated on the example of the phenylalanine-tyrosine metabolism. A healthy child, a patient with phenylketonuria and a patient with hyper phenylalaninemia were loaded with 200 mg/kg of deuterated phenylalanine.
H C, Curtius, J A, Völlmin, K, Baerlocher   +2 more
openaire   +2 more sources

A SIMPLE PHENYLALANINE METHOD FOR DETECTING PHENYLKETONURIA IN LARGE POPULATIONS OF NEWBORN INFANTS.

Pediatrics, 1963
A new method is described for rapid and economical screening of large numbers of hospital nursery infants for elevation in blood phenylalanine associated with phenylketonuria. Results are presented for 682 infants, 96% of whom were 4 days of age. None of
R. Guthrie, Ada Susi
semanticscholar   +1 more source