Results 331 to 340 of about 390,444 (399)

Association between prediagnostic serum metabolites and pancreatic ductal adenocarcinoma risk in two prospective cohorts

International Journal of Cancer, EarlyView.
What's New? Exposures and mechanisms that contribute to and promote pancreatic ductal adenocarcinoma (PDAC) remain unclear. In this study, the authors applied metabolomics to better understand PDAC etiology by examining associations between prediagnostic serum metabolites and PDAC risk.
Ting Zhang, Steven C. Moore, Sheng Fu, Xiaoyu Wang, Demetrius Albanes, Stephanie J. Weinstein, Kai Yu, Rachael Z. Stolzenberg‐Solomon   +7 more
wiley   +1 more source

Multi-omics technology reveals the changes in gut microbiota to stimulate aromatic amino acid metabolism in children with allergic rhinitis and constipation. [PDF]

Front Allergy
Wang C, Liu H, Li X, Kong W, Wu H, Huang C.   +5 more
europepmc   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Impact of a mobile health intervention on health management among children with phenylketonuria based on a multi-theory model of the behavior change wheel theory and family health theory: protocol for a randomized controlled trial. [PDF]

Front Psychiatry
Wang J, Yang S, Wang J, Zhu B, Wang Y, Zhao L, Wang W, Li G, Wang F, Wang X.   +9 more
europepmc   +1 more source

Temporal response patterns of human gut microbiota to dietary fiber

iMeta, EarlyView.
In this study, 19 overweight participants, with or without type 2 diabetes mellitus, underwent 14 days of normal‐diet observation followed by 14 days of dietary fiber intervention. Fecal samples and continuous glucose monitoring data were collected daily throughout the 28‐day period.
Xiaotong Lin, Chaoxun Wang, Biao Liu, Yin Zhu, Rui Zhai, Chenhong Zhang   +5 more
wiley   +1 more source

Changes in L-phenylalanine concentration reflect and predict response to anti-PD-1 treatment combined with chemotherapy in patients with non-small cell lung cancer. [PDF]

MedComm (2020)
Liu Y, Ping Y, Zhang L, Zhao Q, Huo Y, Li C, Shan J, Qi Y, Wang L, Zhang Y.   +9 more
europepmc   +1 more source

An Integrated Analysis of Transcriptomic and Metabolomic Effects Reveals Insights into Stress Responses in Largemouth Bass (<i>Micropterus salmoides</i>) Under MS-222 (Tricaine Methanesulfonate) Exposure. [PDF]

Metabolites
Gao P, Chen R, Ma D, Lin S, Yu H, Zhang X.   +5 more
europepmc   +1 more source

Boron in My Mind: A Comprehensive Review of the Evolution of the Diverse Syntheses of 4-Borono-l-Phenylalanine, the Leading Agent for Boron Neutron Capture Therapy. [PDF]

ChemMedChem
Ahmad S, Pan M, Hayward JJ, Sementilli M, Porter LA, Trant JF.   +5 more
europepmc   +1 more source

Nitisinone desensitization protocol, case report of hereditary Tyrosinemia type 1 with successful treatment and outcomes. [PDF]

Orphanet J Rare Dis
Vallejo M, Villarreal V, Guardiola MA, Bachiller W, Moreno M, Vargas P, López LJ.   +6 more
europepmc   +1 more source

Intra-arterial Administration of Radiopharmaceuticals in Neuro-Oncology; New Improvement for [¹³¹I]-Phenylalanine in High-Grade Gliomas? [PDF]

Cardiovasc Intervent Radiol
Tolboom N, Snijders TJ, Vonken EPA, van der Schaaf IC, Seute T, Braat AJAT.   +5 more
europepmc   +1 more source