Results 291 to 300 of about 178,348 (314)

On the mechanism of action of phenylalanine hydroxylase

Biochemical Society Transactions, 1985
Thomas A. Dix, D. E. Wallick, Stephen J. Benkovic, Paul L. Domanico, Betty J. Gaffney, Stephen O. Pember, L. M. Bloom   +6 more
openaire   +3 more sources

Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat.

Nature Chemical Biology, 2016
Isabelle Becher, Thilo Werner, Carola Doce, E. Zaal, Ina Tögel, Crystal A. Khan, A. Rüger, M. Muelbaier, Elsa Salzer, C. Berkers, P. Fitzpatrick, M. Bantscheff, M. Savitski   +12 more
semanticscholar   +1 more source

Effects of phenylalanine on phenylalanine hydroxylase separation and stability

Biochemical Medicine, 1985
Ennis C. Layne, Rebecca D. Crawford, Samuel P. Bessman   +2 more
openaire   +3 more sources

Tetrahydrobipterin-responsive phenylalanine hydroxylase deficiency

Journal of Human Genetics, 2018
S. Kure, H. Shintaku
semanticscholar   +1 more source

[74] Phenylalanine hydroxylase (Pseudomonas)

1970
Publisher Summary This chapter discusses the assay, purification, and properties of phenylalanine hydroxylase from Pseudomonas. The hydroxylation of phenylalanine to tyrosine is catalyzed by an inducible enzyme from Pseudomonas. This conversion requires molecular oxygen and a tetrahydropteridine.
openaire   +2 more sources

The Mechanism of Action of Phenylalanine Hydroxylase

Annals of the New York Academy of Sciences, 1986
Stephen J. Benkovic, Thomas A. Dix, Betty J. Gaffney, L. M. Bloom, Gideon E. Bollag, Stephen O. Pember   +5 more
openaire   +3 more sources

Modeling correlates of low bone mineral density in patients with phenylalanine hydroxylase deficiency

Journal of Inherited Metabolic Disease, 2016
K. Coakley, T. Douglas, M. Goodman, U. Ramakrishnan, S. Dobrowolski, Rani H. Singh   +5 more
semanticscholar   +1 more source

Co-expression of phenylalanine hydroxylase variants and effects of interallelic complementation on in vitro enzyme activity and genotype-phenotype correlation.

Molecular Genetics and Metabolism, 2016
Nan-ping Shen, Caroline Heintz, C. Thiel, J. Okun, G. Hoffmann, N. Blau   +5 more
semanticscholar   +1 more source

Mapping the functional landscape of frequent phenylalanine hydroxylase (PAH) genotypes promotes personalised medicine in phenylketonuria

Journal of Medical Genetics, 2015
M. Danecka, M. Woidy, J. Zschocke, F. Feillet, A. Muntau, S. Gersting   +5 more
semanticscholar   +1 more source

Phenylalanine Hydroxylase Deficiency

, 2017
D. Regier, C. Greene
semanticscholar   +1 more source