Results 31 to 40 of about 1,849 (201)
The Chemical Record, Volume 25, Issue 12, December 2025.Systematic overview of pyrazole functionalization reactions from C‐5 to N−H. It covers different strategies, from traditional cross‐coupling of prefunctionalized pyrazoles to more efficient direct functionalizations. This review briefly and systematically overviews C–H and N–H functionalization reactions of pyrazoles, aimed at creating new CC and C ...
Karolina Dzedulionytė Müldür +3 more
wiley +1 more source
Hydrogen Peroxide‐Responsive Aminoferrocene Prodrugs
European Journal of Organic Chemistry, Volume 28, Issue 33, September 20, 2025.To improve sensitivity toward H2O2, the boronic acid pinacol ester in known aminoferrocene‐based anticancer prodrug 13b is replaced with an α‐ketamide fragment to obtain prodrug 2a and some of its N‐alkylated derivatives. 2a exhibits substantially improved cytotoxicity in vitro toward ovarian cancer A2780 and Burkitt's lymphoma BL‐2 cells.
Marlies Körber +3 more
wiley +1 more source
Acta Crystallographica Section C, Volume 81, Issue 8, Page 455-461, August 2025.The structure of O‐ethyl N‐phenylthiocarbamate has been redetermined. Layers of hydrogen‐bonded dimers lie parallel to (031). A refinement using nonspherical scattering factors greatly reduced the number and severity of badly‐fitting reflections.The structure of O‐ethyl N‐phenylthiocarbamate, C9H11NOS (2), has been redetermined, confirming the results ...
Peter G. Jones
wiley +1 more source
, 2011 Monosulphides of O-phenyl-N-substituted phenylcar- bamates were prepared by the reaction between O- phenyl-N-substituted phenylcarbamates and sulph- ur dichloride while the corresponding disulphides were prepared by the reaction between O-phenyl-N ...
F. Adelowo, I. Ojo, O. Amuda
semanticscholar +1 more source
Journal of Separation Science, Volume 48, Issue 4, April 2025.ABSTRACT A novel high‐performance liquid chromatography method for the enantioseparation of mirabegron (R‐mirabegron), a selective β‐3 adrenergic receptor agonist, using cyclodextrin (CD)‐based chiral stationary phases (CSPs) was developed. Seven different CSPs containing β‐, γ‐, hydroxypropyl‐β‐, sulfobutyl‐β‐, carboxymethyl‐β‐, permethyl‐β‐, and ...
Ali Mhammad +5 more
wiley +1 more source
Evolution of fungicide resistance in Botrytis cinerea in protected crops in Greece
, 1997 Isolates of Botrytis cinerea Pers.: Fr. from different crops and localities in Greece were compared with reference isolates from France and Israel and classified into various groups on the basis of their sensitivity to dicarboximides and benzimidazoles ...
A.C. Pappas, Pappas, A. C.
core +1 more source
Microbial Biotechnology, Volume 18, Issue 3, March 2025.ABC efflux transporters, which can expel various toxic substances, play an important role in the efflux‐mediated resistance of Botrytis cinerea to multiple fungicides. Effective regulation of the pumps, such as synergistic effects via efflux inhibition, will provide a viable strategy to control the challenge of fungal MDR.
Zhaochen Wu +4 more
wiley +1 more source
Preparation of secondary alcohols of high optical purity
, 1986 Partially resolved enantiomers of optically active alcohols I-V, obtained by enantioselective reduction of the corresponding ketones with lithium aluminium hydride in the presence of (-)-quinine, were converted into crystalline 3,5-dinitrobenzoates or ...
Otakar Červinka +2 more
core +1 more source
Unusually Low Barrier to Carbamate C−N Rotation
, 2016 The barrier for rotation about an N-alkylcarbamate C(carbonyl)−N bond is around 16 kcal/mol. In the case of an N-phenylcarbamate, the rotational barrier is lowered to 12.5 kcal/mol, but with N-(2-pyrimidyl)carbamates the barriers are so low (
Bradley D. Smith (1315578) +5 more
core +2 more sources
Basic &Clinical Pharmacology &Toxicology, Volume 135, Issue 6, Page 755-766, December 2024.Abstract Omeprazole (OME) is a CYP2C19 phenotyping probe, marketed as a racemic (S)/(R) mixture or as an S‐enantiomer. Both CYP2C19 and CYP3A4 enzymes mediate (R)‐OME hydroxylation to (R)‐5‐hydroxyomeprazole, while (S)‐OME is exclusively hydroxylated via CYP2C19.
Kenza Abouir +4 more
wiley +1 more source