Results 91 to 100 of about 51,442 (242)

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, Volume 7, Issue 1, January 2026.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

A Narrative Review of Pheochromocytoma in VHL

Journal of Kidney Cancer and VHL
This systematic review aims to investigate the clinical presentation, diagnostic methods, and management strategies for pheochromocytoma in patients with von Hippel-Lindau (VHL) disease, an autosomal dominant disorder that predisposes individuals to the
Danilo Coco, Silvana Leanza
doaj   +1 more source

Phenothiazine Derivatives and Their Impact on the Apoptosis Processes: A Review

Journal of Applied Toxicology, Volume 46, Issue 1, Page 42-60, January 2026.
ABSTRACT Phenothiazine derivatives have been used for decades as antipsychotic drugs in multiple mental health and physical conditions treatment (schizophrenia, mania in bipolar disorder, and psychosis). Epidemiological studies have shown that people with schizophrenia are less likely to suffer from cancer, which indicates the ability of antipsychotics
Michał Otręba, Łukasz Marek, Piotr Paduszyński, Jerzy Stojko, Anna Rzepecka‐Stojko   +4 more
wiley   +1 more source

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

Medicinal Research Reviews, Volume 46, Issue 1, Page 203-237, January 2026.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller, Nadia Bom Pedersen, Vladimir Shalgunov, Andreas Ingemann Jensen, Umberto Maria Battisti, Matthias Manfred Herth   +5 more
wiley   +1 more source

Pheochromocytoma Crisis Treated with Urapidil: a Case Report

Acta Clinica Croatica
Pheochromocytomas are rare tumors that present with a broad spectrum of symptoms and signs, making differential diagnosis broad. They can cause a pheochromocytoma crisis that manifests with arterial blood pressure oscillations, and subsequent symptoms ...
Miro Bakula, Lea Tomašić, Ivana Kokan, Katarina Mucić, Nikolina Marić, Maja Bakula   +5 more
doaj   +1 more source

Recent developments in eosinophilic renal neoplasms: what's new, true and important?

Histopathology, Volume 88, Issue 1, Page 166-192, January 2026.
Recent developments and acquired knowledge on newer renal entities with eosinophilic cytoplasm opened insights into the clinical, pathological, immunohistochemical, molecular, epidemiological aspects, and the prognosis of these entities. We emphasize the role of routine morphology, aided by appropriate and select immunohistochemistry, as essential keys
Kiril Trpkov, Farshid Siadat, Rola Saleeb   +2 more
wiley   +1 more source

Somatic NF1 inactivation is a frequent event in sporadic pheochromocytoma [PDF]

, 2012
Nelly Burnichon, Alexandre Buffet, Béatrice Parfait, Éric Letouzé, Ingrid Laurendeau, Céline Loriot, Éric Pasmant, Nasséra Abermil, L. Valeyrie‐Allanore, Jérôme Bertherat, Laurence Amar, Dominique Vidaud, Judith Favier, Anne‐Paule Gimenez‐Roqueplo   +13 more
openalex   +1 more source

Ras Homolog Enriched in Brain Protein Reverses Amyloid Beta‐Induced Escape of Inflammatory Cytokine mRNAs From Immunoisolated RNA Processing Bodies of Glioblastoma Cells

The FASEB Journal, Volume 39, Issue 24, 31 December 2025.
A detergent‐based method, combined with immunoprecipitation using an anti‐P‐body component‐specific antibody, was used to isolate RNAs associated with RNA processing bodies (PBs) from both neuronal and glial cells. In neurons, β‐amyloid oligomers helped to trap specific mRNAs related to neuronal differentiation into PBs.
Sritama Ray, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Microarray analysis reveals differential expression of benign and malignant pheochromocytoma [PDF]

, 2010
Jens Waldmann, Volker Fendrich, J Holler, Malte Buchholz, Ernst Heinmöller, Peter Langer, Annette Ramaswamy, Birgit Samans, Martin K. Walz, Μ. Rothmund, Detlef K. Bartsch, Emily P. Slater   +11 more
openalex   +1 more source

Clinical and genetic features of multiple primary tumours cohorts with a renal cell carcinoma: Implications for molecular genetic investigations

International Journal of Cancer, Volume 157, Issue 12, Page 2532-2543, 15 December 2025.
What's New? Current knowledge of the genetic architecture underlying the development of renal cell carcinoma‐related multiple primary tumours is limited. The authors comprehensively analysed the results of exome/genome sequencing cohorts including 534 patients to better define genotype–phenotype correlations.
Huairen Zhang, Bryndis Yngvadottir, Avgi Andreou, Yasemin Cole, Emma R. Woodward, James Whitworth, Eamonn R. Maher   +6 more
wiley   +1 more source