Results 111 to 120 of about 51,442 (242)

Adrenal Myelolipoma Masquerading as Pheochromocytoma [PDF]

, 2012
N. Lynn Ferguson, Keith D. Gray, Amila Orucevic   +2 more
openalex   +1 more source

Comprehensive Molecular Screening by Next Generation Sequencing of Gastrointestinal Stromal Tumors (GISTs): In Silico Analysis and Classification of Rare KIT Exon 11 Mutations

Cancer Medicine, Volume 14, Issue 23, December 2025.
ABSTRACT Introduction Gastrointestinal stromal tumors (GISTs) originate from mesenchymal precursor cells of the gastrointestinal wall and account for approximately 3% of all gastrointestinal malignancies. In adults, these tumors most commonly harbor mutually exclusive activating mutations in KIT, PDGFRA, BRAF, or SDH‐family genes.
Maria Grazia Rodriquenz, Barbara Pasculli, Michelina Rendina, Francesco Petrizzelli, Tommaso Mazza, Antonio Petracca, Bartolomeo Augello, Michelina Coco, Teresa Balsamo, Anna Troiano, Magda Zanelli, Evaristo Maiello, Paolo Graziano, Paola Parente, Paola Parrella   +14 more
wiley   +1 more source

Incidental detection of purely cystic pheochromocytoma in a young adult presenting with lower urinary tract infection

Radiology Case Reports
Pheochromocytoma is a rare neuroendocrine tumor arising from adrenal medulla. Patients usually show classic triad of headache, palpitations and diaphoresis along with persistent or paroxysmal hypertension.
Neha Singh, MD, Kishan Kumar Thakur, MD, Shalikh Moidu, MCh, Nidhi Anand, MD   +3 more
doaj   +1 more source

Diagnostic Challenges of Adrenal Venous Sampling for Primary Hyperaldosteronism in a Patient With Subclinical Cushing's Syndrome: A Case Report

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Hypertension is a significant comorbidity in the New World, and its prevalence is rising. Around 5%–10% of cases with hypertension have secondary hypertension. Adrenal gland disease is among the common causes of secondary hypertension. We present a 57‐year‐old male with uncontrolled hypertension and a history of intracranial hemorrhage.
Mahsa Malekian, Vahide Sadra, Amir Bahrami, Javad Jalili, Hamidreza Ashayeri   +4 more
wiley   +1 more source

Targeting CD70 in cancer: Mechanisms of immune escape and translational opportunities

Clinical and Translational Discovery, Volume 5, Issue 6, December 2025.
Hypoxia, oncogenic signaling (e.g., MAPK, STAT3), and histone modifications promote CD70 overexpression in cancer cells. Viral infections like EBV and HTLV‐1 induce CD70 expression in tumor and transformed immune cells. Tyrosine kinase inhibitors and chemotherapeutic agents induce CD70 expression through therapy‐related stress in cancer cells ...
Akash Sabarwal, Saba Tabasum, Laxminarayan Rawat, Soumitro Pal   +3 more
wiley   +1 more source

Predictive Factors of Malignancy in Cervical Paragangliomas: A Retrospective Study

Head &Neck, Volume 47, Issue 12, Page 3340-3348, December 2025.
ABSTRACT Background Early predictive factors of metastatic cervical paragangliomas (cPG) are lacking. Methods This multicenter retrospective study included patients with at least one cPG. Metastatic cPG were defined by the histological presence of lymph node metastases or distant metastases.
Garance Haw, Maxime Fieux, Anthime Flaus, Hélène Lasolle, Juliette Abeillon, Myriam Decaussin‐Petrucci, Dylan Pavie, Benjamin Verillaud, Philippe Herman, Patrick Feugier, Fatima Ameur, Pierre Philouze, Françoise Borson‐Chazot, Philippe Ceruse   +13 more
wiley   +1 more source

Development and Characterization of a Tunable PDMS Substrate Model for Investigating Elastic Properties and Mechanical Stretching in Intervertebral Disc Cells

JOR SPINE, Volume 8, Issue 4, December 2025.
This study introduces a tunable PDMS stretching platform to examine annulus fibrosus cell responses to combined substrate stiffness and mechanical loading. By integrating a Sylgard 184/527 mix, the platform provides a stiffness range of 9–240 kPa and enables cyclic strain application while preserving viability with stiffness‐ and strain‐dependent ...
Johannes Hasler, Mikkael Lamoca, Kory Schimmelpfennig, Shuhuan Zhang, Wolfgang Hitzl, Sami Farajollahi, Vinay V. Abhyankar, Christopher L. Lewis, Rui Liu, Karin Wuertz‐Kozak   +9 more
wiley   +1 more source

Aluminum Exposure Impairs Electrochemically Measured Vesicular Storage and Exocytosis via Iron Homeostasis Dysregulation

Angewandte Chemie, Volume 137, Issue 48, November 24, 2025.
Al3+ competes with Fe3+ for transferrin (Tf) binding and enters cells via transferrin receptor (TfR)‐mediated endocytosis, disrupting cellular iron homeostasis. Intracellular vesicle impact electrochemical cytometry (IVIEC) and single‐cell amperometry (SCA), which record the oxidation of dopamine, reveal increased neurotransmitter storage and ...
Shi‐Hua Chen, Chaoyi Gu, Xing‐Jiu Huang, Andrew G. Ewing   +3 more
wiley   +2 more sources

Succinate Dehydrogenase Pathogenic Variants Among Older Adults With Head and Neck Paragangliomas

Laryngoscope Investigative Otolaryngology, Volume 10, Issue 6, December 2025.
The objective of this study was to determine the proportion of patients over the age of 50 who have head and neck paraganglioma related to an SDH pathogenic variant. The rate of SDH PVs in the tested group was 25%. Thus, older patients with HNPGL and their families should still be referred for genetic testing.
Nikhil Bellamkonda, Anne Naumer, Luke O. Buchmann, Hilary C. McCrary, Mana Espahbodi, Neil S. Patel   +5 more
wiley   +1 more source

Systematic genetic screening in a prospective group of Danish patients with pheochromocytoma

Research and Reports in Urology, 2017
Morten Steen Svarer Hansen,1 Niels Jacobsen,1 Anja Lisbeth Frederiksen,2 Lars Lund,3 Marianne Skovsager Andersen,1 Dorte Glintborg1 1Department of Endocrinology and Metabolism, 2Department of Clinical Genetics, 3Department of Urology, Odense University ...
Hansen MSS, Jacobsen N, Frederiksen AL, Lund L, Andersen MS, Glintborg D   +5 more
doaj