Results 91 to 100 of about 6,876 (236)
Burosumab in Unidentifiable Tumor‐Induced Osteomalacia
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT Tumor‐induced osteomalacia (TIO) can be challenging due to underlying tumors being either unresectable or unidentifiable. Burosumab, an anti‐FGF23 monoclonal antibody, has been proven to be effective in treating TIO but is currently not subsidized for this indication in Australia.
Yi Shan Der +5 more
wiley +1 more source
Journal of Investigative Medicine High Impact Case Reports, 2015 Loss-of-function mutations in the p hosphate regulating gene with h omologies to e ndopeptidases on the X -chromosome ( PHEX ) have been causally associated with X-linked hypophosphatemic rickets (XLHR).
Kok Siong Poon BSc +4 more
doaj +1 more source
X - Linked Hypophosphatemic Rickets: A diagnostic and therapeutic challenge
Iatreia, 2021 X-linked hypophosphatemia is a genetic disorder caused by PHEX gene mutations, which affects the encoding of a metalloprotease whose function is to inhibit fibroblastic growth factor —23 (FGF-23), promoting phosphate renal loss.
Guerrero Tinoco, Gustavo Adolfo +2 more
doaj +1 more source
The FEBS Journal, Volume 293, Issue 1, Page 42-70, January 2026.This guide proposes a roadmap combining state‐of‐the‐art computational and experimental approaches (including biophysical, biochemical, and imaging techniques) to identify, characterize, and contextualize extracellular matrix (ECM) protein interactions.
Leanna Leverton +4 more
wiley +1 more source
Electron density distribution in paramagnetic chromium A gamma ray diffraction study [PDF]
, 2006 High accuracy single crystal structure factors, complete up to sin amp; 61553; amp; 61548; amp; 61472; amp; 61501; amp; 61472; amp; 61489; amp; 61486; amp; 61495; amp; 61496; amp; 61472; amp; 61485; amp; 61489; amp; 61484; amp; 61472; have been ...
Jauch, W., Reehuis, M.
core +3 more sources
Physics-based analysis of Affymetrix microarray data
, 2006 We analyze publicly available data on Affymetrix microarrays spike-in experiments on the human HGU133 chipset in which sequences are added in solution at known concentrations. The spike-in set contains sequences of bacterial, human and artificial origin.
Barkema, G. T. +3 more
core +1 more source
Iron and fibroblast growth factor 23 in X-linked hypophosphatemia [PDF]
, 2014 Background Excess fibroblast growth factor 23 (FGF23) causes hypophosphatemia in autosomal dominant hypophosphatemic rickets (ADHR) and X-linked hypophosphatemia (XLH). Iron status influences C-terminal FGF23 (incorporating fragments plus intact FGF23)
Econs, Michael J. +3 more
core +1 more source
Exploring neuronal mechanisms of osteosarcopenia in older adults
The Journal of Physiology, Volume 604, Issue 2, Page 672-688, 15 January 2026.Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley +1 more source
New Spiked-In Probe Sets for the Affymetrix HGU-133A Latin Square Experiment [PDF]
, 2006 The Affymetrix HGU-133A spike in data set has been used for determining the sensitivity and specificity of various methods for the analysis of microarray data.
Chen, Zhongxue, McGee, Monnie
core +1 more source
Lifelong challenge of calcium homeostasis in male mice lacking TRPV5 leads to changes in bone and calcium metabolism [PDF]
, 2016 Trpv5 plays an important role in calcium (Ca2+) homeostasis, among others by mediating renal calcium reabsorption. Accordingly, Trpv5 deficiency strongly stresses Ca2+ homeostasis in order to maintain stable serum Ca2+.
Bindels, R.J.M. (René) +12 more
core +3 more sources