Results 101 to 110 of about 6,876 (236)
Hypophosphatemic Rickets in Patients from Bichoric Biamniotic Twins: A Case Report
Педиатрическая фармакологияBackground. X-linked dominant hypophosphatemic rickets (X-linked hypophosphatemia, XLH) is a disease caused by mutations in the PHEX gene (located at the Xp22.1 locus), which encodes an enzyme bound to the cell surface that cleaves the protein phosphate ...
Anna S. Nechaeva +5 more
doaj +1 more source
X-linked hypophosphatemic rickets: Case report [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2014 Introduction. X-linked hypophosphatemic rickets (XLHR) is a dominant inherited disease caused by isolated renal phosphate wasting and impairment of vitamin D activation.
Radlović Vladimir +6 more
doaj +1 more source
Extracellular matrix of dental pulp stem cells: applications in pulp tissue engineering using somatic MSCs [PDF]
, 2014 Dental Caries affects approximately 90% of the world's population. At present, the clinical treatment for dental caries is root canal therapy. This treatment results in loss of tooth sensitivity and vitality. Tissue engineering can potentially solve this
Anne George +2 more
core +2 more sources
The Aging Landscape by scRNAseq of Mesenchymal Lineage Cells in Mouse Bone
Aging Cell, Volume 24, Issue 12, December 2025.scRNA‐seq analysis reveals age‐related changes in bone mesenchymal cells in male and female mice. Moreover, the comparison of aging and autophagy deficiency in bone mesenchymal cells shows overlap and suggests that age‐related decline in autophagy contributes to skeletal aging.
Melda Onal +12 more
wiley +1 more source
JCI Insight, 2022 Patients with the renal phosphate–wasting disease X-linked hypophosphatemia (XLH) and Hyp mice, the murine homolog of XLH, are characterized by loss-of-function mutations in phosphate-regulating endopeptidase homolog X-linked (PHEX), leading to excessive
Achim Buck +4 more
doaj +1 more source
NMR in Biomedicine, Volume 38, Issue 10, October 2025.The kinetics of the creatine CH2 resonance (Cr‐CH2) and phosphocreatine (PCr) during muscle exercise and recovery were studied using interleaved 1H and 31P MRS at 7T in 27 volunteers. The two methods exhibit no differences in depletion and recovery time constants.
Radka Klepochová +8 more
wiley +1 more source
Recent Progress in Osteocyte Research [PDF]
, 2013 The last decade has seen an exponential increase in our understanding of osteocytes function and biology. These cells, once considered inert by-standers trapped into the mineralized bone, has now risen to be key regulators of skeletal metabolism, mineral
Divieti Pajevic, Paola
core +2 more sources
New insights into NPP1 function:Lessons from clinical and animal studies [PDF]
, 2012 The recent elucidation of rare human genetic disorders resulting from mutations in ectonucleotide pyrophosphotase/phosphodiesterase (ENPP1), also known as plasma cell membrane glycoprotein 1 (PC-1), has highlighted the vital importance of this molecule ...
Huesa, C +3 more
core +1 more source
Phosphate in Physiological and Pathological Mineralization: Important yet Often Unheeded
MedComm, Volume 6, Issue 7, July 2025.Phosphate serves as a building block for physiological mineralization, and as a signaling molecule that regulates the activity of mineralizing cells. The disturbance in these processes could induce a series of pathological mineralization, with abnormal mineralization of hard tissues and ectopic mineralization of soft tissues being the most ...
Wen Qin +8 more
wiley +1 more source
Irisin Prevents the Effects of Simulated Microgravity on Bone and Muscle Differentiation Markers
FASEB BioAdvances, Volume 7, Issue 7, July 2025.In the RPM condition, irisin treatment reduces the expression of key genes involved in the myogenesis process and increases those of osteocyte differentiation. ABSTRACT Microgravity exposure affects both tissues and cells, and, in this regard, one of the most affected targets is the skeletal muscle system due to the significant loss of bone and muscle ...
Lorenzo Sanesi +10 more
wiley +1 more source