Results 111 to 120 of about 6,876 (236)

Common distribution of gad operon in Lactobacillus brevis and its GadA contributes to efficient GABA synthesis toward cytosolic near-neutral pH [PDF]

, 2017
published_or_final_versio
Khafipour, E, Law YS, Shah, N, Tun, HM, Wu, Q   +4 more
core   +1 more source

ASARM peptides: PHEX-dependent and -independent regulation of serum phosphate

American Journal of Physiology-Renal Physiology, 2011
Increased acidic serine aspartate-rich MEPE-associated motif (ASARM) peptides cause mineralization defects in X-linked hypophosphatemic rickets mice (HYP) and “directly” inhibit renal phosphate uptake in vitro. However, ASARM peptides also bind to phosphate-regulating gene with homologies to endopeptidases on the X chromosome (PHEX) and are a ...
Valentin, David, Aline, Martin, Anne-Marie, Hedge, Marc K, Drezner, Peter S N, Rowe   +4 more
openaire   +3 more sources

Chiral Amplification and Regulation: Design and Applications of Circularly Polarized Luminescence‐Active Materials Derived From Macrocyclic Compounds

Aggregate, Volume 6, Issue 6, June 2025.
The graphical abstract highlights the key concepts of this review, including chiral transfer and amplification mechanisms, macrocyclic compounds, circularly polarized luminescence (CPL) applications, chiral sensing, asymmetric catalysis, and stimuli‐responsive applications.
Wei Zhang, Mao‐Qin Liu, Yang Luo
wiley   +1 more source

Organic rankine cycle modelling and the ORCmKit library: analysis of R1234ze(Z) as drop-in replacement of R245fa for low-grade waste heat recovery [PDF]

, 2016
Due to the wide interest in organic Rankine cycles (ORCs) as a sustainable technology and the importance of numerical analyses and optimization procedures while considering such systems, we created a dedicated open-source library named “ORC modelling Kit”
De Paepe, Michel, Dickes, Remi, Lemort, Vincent, Quoilin, Sylvain, van den Broek, Martijn, Ziviani, Davide   +5 more
core   +1 more source

The chicken or the egg: PHEX, FGF23 and SIBLINGs unscrambled [PDF]

Cell Biochemistry and Function, 2012
The eggshell is an ancient innovation that helped the vertebrates' transition from the oceans and gain dominion over the land. Coincident with this conquest, several new eggshell and noncollagenous bone‐matrix proteins (NCPs) emerged. The protein ovocleidin‐116 is one of these proteins with an ancestry stretching back to the Triassic. Ovocleidin‐116 is
openaire   +2 more sources

X‐Linked Hypophosphataemia and Burosumab: A Systemic Disease With a New Treatment

Journal of Paediatrics and Child Health, Volume 61, Issue 5, Page 685-700, May 2025.
ABSTRACT X linked hypophosphataemia (XLH) is a systemic, chronic condition that significantly impairs quality of life. In XLH, a phosphate regulating endopeptidase homologue X‐linked (PHEX) gene mutation leads to excess fibroblast growth factor 23 (FGF23), causing hypophosphataemia and subsequent rickets, lower limb deformity, pain and other sequelae ...
Jessica L. Sandy, Andrew Biggin, Aris Siafarikas, Peter J. Simm, Christine P. Rodda, Craig F. Munns   +5 more
wiley   +1 more source

Fosfaattiaineenvaihdunnan säätely ja häiriöt [PDF]

, 2016
•La­bo­ra­to­riossa mi­tattu plasman fos­fori ku­vaa pääo­sin fos­faattia. Klii­ni­sessä työs­sä ter­mejä ”fos­fori” ja ”fos­faatti” käy­tetään usein syno­nyy­meinä. •Plasman fos­faatti hei­jastaa huo­nosti ko­ko ke­hon fosfaat­ti­va­ras­toja.
Koistinen, Heikki, Miettinen, Helena
core  

Genetic diseases of renal phosphate handling [PDF]

, 2017
UNLABELLED: Renal control of systemic phosphate homeostasis is critical as evident from inborn and acquired diseases causing renal phosphate wasting. At least three transport proteins are responsible for renal phosphate reabsorption: NAPI-IIa (SLC34A1 ...
Biber, Jürg, Hernando, Nati, Rubio-Aliaga, Isabel, Wagner, Carsten A.   +3 more
core   +3 more sources

Panel 3 : Genetics and Precision Medicine of Otitis Media [PDF]

, 2017
Objective. The objective is to perform a comprehensive review of the literature up to 2015 on the genetics and precision medicine relevant to otitis media. Data Sources. PubMed database of the National Library of Medicine. Review Methods.
Brown, Steve, Hafren, Lena, Huang, Qiuhong, Kerschner, Joseph, Li, Jian-Dong, Lin, Jizhen, Nakamura, Yoshihisa, Preciado, Diego, Zhang, Yan, Zheng, Qing Y.   +9 more
core   +1 more source

Kbus/Idr, a mutant mouse strain with skeletal abnormalities and hypophosphatemia: Identification as an allele of 'Hyp'

Journal of Biomedical Science, 2011
Background The endopeptidase encoded by Phex (phosphate-regulating gene with homologies to endopeptidases linked to the X chromosome) is critical for regulation of bone matrix mineralization and phosphate homeostasis.
Kimura Atsushi, Ogiwara Katsueki, Yoshiki Atsushi, Mekada Kazuyuki, Hanai Atsuko, Moriyama Kenji, Takahashi Takayuki   +6 more
doaj   +1 more source