Results 51 to 60 of about 6,876 (236)
Frontiers in Pediatrics, 2023 AimX-linked hypophosphatemia (XLH) is the most common inherited form of rickets, and it is caused by pathogenic inactivating variants of the phosphate-regulating endopeptidase homolog X-linked (PHEX) gene.
Mauro Borghi +4 more
doaj +1 more source
Osteocytes Serve as a Progenitor Cell of Osteosarcoma [PDF]
, 2014 Osteosarcoma (OSA) is the most common primary bone tumor in humans. However, the cell of origin of OSA is not clearly defined although there is evidence that osteoblasts may serve as OSA progenitors.
Asai +49 more
core +1 more source
Cloning and Characterization of the Proximal MurinePhexPromoter [PDF]
Endocrinology, 2001 Phex is an endopetidase that regulates systemic phosphate homeostasis. We investigated Phex gene transcription by cloning and performing functional analysis of the 2736 bp of the 5' flanking region of the mouse Phex gene containing its promoter. We identified a transcription start site, a consensus TATA-box, and multiple potential cis-acting regulator ...
S, Liu, R, Guo, L D, Quarles
openaire +3 more sources
A Novel Gene Mutation in a Patient with Sporadic Hypophosphatemic Rickets [PDF]
Endocrinology and Metabolism, 2014 Phosphate regulating gene with homologies to endopeptidases on the X-chromosome (PHEX) is a common cause of X-linked hypophosphatemic (XLH) rickets. Diverse PHEX gene mutations have been reported; however, gene mutations in sporadic rickets are less ...
Yea Eun Kang +6 more
doaj +1 more source
Medicina, 2023 The present study aimed to demonstrate the immunolocalization and/or gene expressions of the enzymes and membrane transporters involved in bone mineralization after the intermittent administration of parathyroid hormone (PTH).
Takahito Mae +7 more
doaj +1 more source
Extracellular Matrix Mineralization Promotes E11/gp38 Glycoprotein Expression and Drives Osteocytic Differentiation [PDF]
, 2012 Osteocytes are terminally differentiated osteoblasts which reside in a mineralized extracellular matrix (ECM). The factors that regulate this differentiation process are unknown.
Farquharson, C. +3 more
core +3 more sources
Probabilistic Label Relation Graphs with Ising Models
, 2015 We consider classification problems in which the label space has structure. A common example is hierarchical label spaces, corresponding to the case where one label subsumes another (e.g., animal subsumes dog).
Deng, Jia +3 more
core +1 more source
Vitamin D. a dynamic molecule. how relevant might the dynamism for a vitamin be [PDF]
, 2015 Cholecalciferol, the precursor of Vitamin D3, is a very old, highly conserved, molecule. Its presence is evident in non-mineralized 750 million-year-old living species, such as plankton.
Mazzaferro, Sandro, Pasquali, Marzia
core +2 more sources
Weakly nonlinear theory of grain boundary motion in patterns with crystalline symmetry
, 2002 We study the motion of a grain boundary separating two otherwise stationary domains of hexagonal symmetry. Starting from an order parameter equation appropriate for hexagonal patterns, a multiple scale analysis leads to an analytical equation of motion ...
A. Kosevich +9 more
core +1 more source
Conditional Deletion of Murine Fgf23: Interruption of the Normal Skeletal Responses to Phosphate Challenge and Rescue of Genetic Hypophosphatemia [PDF]
, 2016 The transgenic and knockout (KO) animals involving Fgf23 have been highly informative in defining novel aspects of mineral metabolism, but are limited by shortened lifespan, inability of spatial/temporal FGF23 control, and infertility of the global KO ...
Allen, Matthew R. +6 more
core +1 more source