Results 91 to 100 of about 5,354 (221)
Clinical and Genetic Characteristics of 153 Chinese Patients With X-Linked Hypophosphatemia
Frontiers in Cell and Developmental Biology, 2021 X-linked hypophosphatemia (XLH) is caused by inactivating mutations in the phosphate-regulating endopeptidase homolog, X-linked (PHEX) gene, resulting in an excess of circulating intact fibroblast growth factor-23 (iFGF-23) and a waste of renal phosphate.
Xiaoyun Lin +3 more
doaj +1 more source
Iron and fibroblast growth factor 23 in X-linked hypophosphatemia [PDF]
, 2014 Background Excess fibroblast growth factor 23 (FGF23) causes hypophosphatemia in autosomal dominant hypophosphatemic rickets (ADHR) and X-linked hypophosphatemia (XLH). Iron status influences C-terminal FGF23 (incorporating fragments plus intact FGF23)
Econs, Michael J. +3 more
core +1 more source
MEPE-derived ASARM peptide inhibits odontogenic differentiation of dental pulp stem cells and impairs mineralization in tooth models of X-linked hypophosphatemia. [PDF]
PLoS ONE, 2013 Mutations in PHEX (phosphate-regulating gene with homologies to endopeptidases on the X-chromosome) cause X-linked familial hypophosphatemic rickets (XLH), a disorder having severe bone and tooth dentin mineralization defects.
Benjamin Salmon +17 more
doaj +1 more source
Common distribution of gad operon in Lactobacillus brevis and its GadA contributes to efficient GABA synthesis toward cytosolic near-neutral pH [PDF]
, 2017 published_or_final_versio
Khafipour, E +4 more
core +1 more source
Burosumab in Unidentifiable Tumor‐Induced Osteomalacia
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT Tumor‐induced osteomalacia (TIO) can be challenging due to underlying tumors being either unresectable or unidentifiable. Burosumab, an anti‐FGF23 monoclonal antibody, has been proven to be effective in treating TIO but is currently not subsidized for this indication in Australia.
Yi Shan Der +5 more
wiley +1 more source
Differing responses of osteogenic cell lines to β-glycerophosphate
Scientific Reports, 2023 Ascorbic acid (Asc), dexamethasone (Dex) and β-glycerophosphate (β-Gly) are commonly used to promote osteogenic behaviour by osteoblasts in vitro. According to the literature, several osteosarcoma cells lines appear to respond differently to the latter ...
Olga S. Yevlashevskaya +3 more
doaj +1 more source
Roles of osteocytes in phosphate metabolism
Frontiers in Endocrinology, 2022 Osteocytes are dendritic cells in the mineralized bone matrix that descend from osteoblasts. They play critical roles in controlling bone mass through the production of sclerostin, an inhibitor of bone formation, and receptor activator of nuclear factor ...
Toshimi Michigami
doaj +1 more source
The FEBS Journal, Volume 293, Issue 1, Page 42-70, January 2026.This guide proposes a roadmap combining state‐of‐the‐art computational and experimental approaches (including biophysical, biochemical, and imaging techniques) to identify, characterize, and contextualize extracellular matrix (ECM) protein interactions.
Leanna Leverton +4 more
wiley +1 more source
Panel 3 : Genetics and Precision Medicine of Otitis Media [PDF]
, 2017 Objective. The objective is to perform a comprehensive review of the literature up to 2015 on the genetics and precision medicine relevant to otitis media. Data Sources. PubMed database of the National Library of Medicine. Review Methods.
Brown, Steve +9 more
core +1 more source
Exploring neuronal mechanisms of osteosarcopenia in older adults
The Journal of Physiology, Volume 604, Issue 2, Page 672-688, 15 January 2026.Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley +1 more source