Results 111 to 120 of about 5,354 (221)
Genetic Comparison of Stemness of Human Umbilical Cord and Dental Pulp [PDF]
, 2016 published_or_final_versio
Choi, BJ +7 more
core +4 more sources
The Journal of Clinical Pharmacology, Volume 65, Issue 2, Page 253-260, February 2025.Abstract X‐linked hypophosphatemia (XLH) is a rare genetic disorder caused by excessive fibroblast growth factor 23 (FGF23), leading to low serum phosphate levels resulting in increased risk of fractures and pseudofractures. Burosumab is indicated for the treatment of XLH.
Krina Mehta +7 more
wiley +1 more source
Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological Disorders. [PDF]
, 2017 The complexity of the traumatic brain injury (TBI) pathology, particularly concussive injury, is a serious obstacle for diagnosis, treatment, and long-term prognosis. Here we utilize modern systems biology in a rodent model of concussive injury to gain a
Agrawal, Rahul +5 more
core +2 more sources
Advances of New Extracellular Vesicle Isolation and Detection Technologies in Cancer Diagnosis
Small, Volume 21, Issue 4, January 29, 2025.Extracellular vesicles (EVs) are a type of phospholipid bilayer vesicles secreted by cells and hold promise for cancer diagnosis. Here, the advantages and limitations of traditional EV detection technologies are reviewed, and the review focuses on emerging EV detection and isolation technologies in cancer diagnosis and explores the perspectives of new ...
Zhihan Liu +5 more
wiley +1 more source
Journal of Biomedical Science, 2011 Background The endopeptidase encoded by Phex (phosphate-regulating gene with homologies to endopeptidases linked to the X chromosome) is critical for regulation of bone matrix mineralization and phosphate homeostasis.
Kimura Atsushi +6 more
doaj +1 more source
In Vivo determination of intracellular pH using pHLuorin proteins in Fusarium Oxysporum [PDF]
, 2016 Premio extraordinario de Trabajo Fin de Máster curso 2013-2014. Molecular and Cellular, Biotechnology and Genetics.El pH extracelular juega un papel clave en los niveles de fosforilación de las MAP quinasas de Fusarium oxysporum.
Serrano Salces, Antonio
core
Clinical Pharmacology &Therapeutics, Volume 116, Issue 5, Page 1343-1351, November 2024.Burosumab is indicated for treatment of a rare bone disease, X‐linked hypophosphatemia (XLH). The aim of this analysis was to evaluate the relationship between a treatment response biomarker and patient‐reported outcomes (PROs). Longitudinal data for PROs were obtained from adults with XLH from a phase III study.
Krina Mehta +6 more
wiley +1 more source
Transcriptional Profiling of PRKG2-Null Growth Plate Identifies Putative Down-Stream Targets of PRKG2 [PDF]
, 2015 Kinase activity of cGMP-dependent, type II, protein kinase (PRKG2) is required for the proliferative to hypertrophic transition of growth plate chondrocytes during endochondral ossification.
Cooper, Vickie +5 more
core +3 more sources
Characterization of a New M13 Metallopeptidase from Deep-Sea Shewanella sp. E525-6 and Mechanistic Insight into Its Catalysis [PDF]
, 2016 Bacterial extracellular peptidases are important for bacterial nutrition and organic nitrogen degradation in the ocean. While many peptidases of the M13 family from terrestrial animals and bacteria are studied, there has been no report on M13 peptidases ...
Bai-Cheng Zhou +9 more
core +2 more sources
Genetic Risk Factors for Atypical Femoral Fractures (AFFs): A Systematic Review [PDF]
, 2018 Atypical femoral fractures (AFFs) are uncommon and have been associated particularly with long-term antiresorptive therapy, including bisphosphonates. Although the pathogenesis of AFFs is unknown, their identification in bisphosphonate-naïve individuals ...
Ebeling, P. (Peter) +5 more
core +3 more sources