Results 21 to 30 of about 347 (94)
Periodontology 2000, Volume 86, Issue 1, Page 79-96, June 2021., 2021 Abstract Oral bacteriophages (or phages), especially periodontal ones, constitute a growing area of interest, but research on oral phages is still in its infancy. Phages are bacterial viruses that may persist as intracellular parasitic deoxyribonucleic acid (DNA) or use bacterial metabolism to replicate and cause bacterial lysis.
Szymon P. Szafrański +2 more
wiley +1 more source
Dual Active Site in the Endolytic Transglycosylase gp144 of Bacteriophage phiKZ [PDF]
Acta Naturae, 2017 Lytic transglycosylases are abundant peptidoglycan lysing enzymes that degrade the heteropolymers of bacterial cell walls in metabolic processes or in the course of a bacteriophage infection. The conventional catalytic mechanism of transglycosylases involves only the Glu or Asp residue.
O V, Chertkov +7 more
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Frontiers in Microbiology, 2022 The development of new antimicrobial agents is critically needed due to the alarming increase in antibiotic resistance in bacterial pathogens. Phages have been widely considered as effective alternatives to antibiotics.
Bingyan Zhang +7 more
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Вопросы вирусологии, 2022 Introduction. Giant phiKZ-like bacteriophages have a unique protein formation inside the capsid, an inner body (IB) with supercoiled DNA molecule wrapped around it.
T. S. Trifonova +6 more
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Genomic transfer via membrane vesicle: a strategy of giant phage phiKZ for early infection. [PDF]
J VirolABSTRACT During infection, the giant phiKZ phage forms a specialized structure at the center of the host cell called the phage nucleus. This structure is crucial for safeguarding viral DNA against bacterial nucleases and for segregating the transcriptional activities of late genes.
Antonova D +13 more
europepmc +4 more sources
Characterization and Genomic Analysis of PALS2, a Novel Staphylococcus Jumbo Bacteriophage
Frontiers in Microbiology, 2021 Staphylococcus aureus is an important human pathogen that can be frequently encountered in clinical and food-processing surroundings. Among the various countermeasures, bacteriophages have been considered to be promising alternatives to antibiotics.
Yoona Lee +9 more
doaj +1 more source
Environmental Microbiology, Volume 22, Issue 6, Page 2165-2181, June 2020., 2020 Summary Pseudomonas virus vB_PaeM_PA5oct is proposed as a model jumbo bacteriophage to investigate phage‐bacteria interactions and is a candidate for phage therapy applications. Combining hybrid sequencing, RNA‐Seq and mass spectrometry allowed us to accurately annotate its 286,783 bp genome with 461 coding regions including four non‐coding RNAs ...
Cédric Lood +9 more
wiley +1 more source
For analyzing the subcellular location of phiKZ phage nucleus
, 2022 The python code was used to generate the distribution of the subcellular location of the phage nucleus for WT phiKZ, mutant phuZ, and phuZ complemented in trans.
Guan, Jingwen +5 more
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Эпидемиология и вакцинопрофилактика, 2018 Relevance. Biofilms of bacteria, in particular, pathogens of purulent-septic and enteral diseases, play an important role in the development of the infectious process, resulting in 60–70% of its chronic and recurrent forms.
O. A. Polygach +2 more
doaj +1 more source
Crystal structure and location of gp131 in the bacteriophage phiKZ virion
Virology, 2012 Pseudomonas phage ϕKZ and its two close relatives ϕPA3 and 201ϕ2-1 are very large bacteriophages that form a separate branch in phage classification because their genomes are very different from the rest of GenBank sequence data. The contractile tail of ϕKZ is built from at least 32 different proteins, but a definitive structural function is assigned ...
Sycheva LV +5 more
openaire +2 more sources