Results 21 to 30 of about 741 (150)

Dual Active Site in the Endolytic Transglycosylase gp144 of Bacteriophage phiKZ [PDF]

Acta Naturae, 2017
Lytic transglycosylases are abundant peptidoglycan lysing enzymes that degrade the heteropolymers of bacterial cell walls in metabolic processes or in the course of a bacteriophage infection.
O. V. Chertkov, G. A. Armeev, I. Uporov, S. A. Legotsky, N. Sykilinda, A. Shaytan, N. Klyachko, Konstantin A. Miroshnikov   +7 more
semanticscholar   +5 more sources

Assessing the transcriptional landscape of Pseudomonas phage 201ϕ2-1: Uncovering the small regulatory details of a giant phage. [PDF]

Microb Biotechnol
Transcriptomic studies on jumbo phages have been limited. From a phage biology perspective, insights into their transcriptome will improve our understanding of how they regulate their infection cycle. Moreover, phage transcriptomic studies are valuable for sourcing regulatory elements which can be exploited in microbial synthetic biology to tune gene ...
Poppeliers J, Focquet M, Boon M, De Mey M, Thomas J, Lavigne R.   +5 more
europepmc   +2 more sources

Investigation of PhiKZ phage therapy against Pseudomonas aeruginosa in mouse pneumonia model

TURKISH JOURNAL OF MEDICAL SCIENCES, 2018
Background/aim: The aim of this study was to investigate the effects of PhiKZ phage therapy and meropenem alone or combined treatments in a pneumonia mouse model induced by the Pseudomonas aeruginosa PAO1 strain.
K. Can, U. Aksu, O. Yenen
semanticscholar   +4 more sources

Characterization of fluorescent proteins for STUdying the morphological rearrangements inside single bacterial cells during infection with phiKZ bacteriophage

St. Petersburg Polytechnical University Journal: Physics and Mathematics, 2022
This work deals with evaluation of key properties of some fluorescent proteins (FPs) in order to use them for observation of redistributing the target proteins between the cytoplasm and pseudonucleus forming in bacterial cell infection by bacteriophage
Antonova Daria, Zotova Anastasia, Usatykh Andrey, Morozova Natalia, Yakunina Maria   +4 more
doaj   +3 more sources

Classification of Myoviridae bacteriophages using protein sequence similarity [PDF]

BMC Microbiology, 2009
Background We advocate unifying classical and genomic classification of bacteriophages by integration of proteomic data and physicochemical parameters. Our previous application of this approach to the entirely sequenced members of the Podoviridae fully ...
Ackermann Hans W, Nilsson Anders S, Mahadevan Padmanabhan, Seto Donald, Summer Elizabeth J, Darius Paul, Lavigne Rob, Kropinski Andrew M   +7 more
doaj   +5 more sources

Electron Tomography Revealed Compact DNA in the Nucleus-like Compartment, Formed in the Bacterial Cell During Infection by the phiKZ Bacteriophage [PDF]

Microscopy and Microanalysis, 2020
PhiKZ-like phages belong to the Myoviridae family and infect the opportunistic pathogenic bacterium Pseudomonas aeruginosa. Notably, phiKZ infection is sustainable against all known bacterial defence systems based on double-stranded DNA damage [1 ...
Yana Danilova, M. Yakunina, A. Moiseenko, V. Belousova, I. Vishnyakov, O. Sokolova   +5 more
semanticscholar   +2 more sources

Factors Influencing the Synonymous Codon and Amino Acid Usage Bias in AT-rich Pseudomonas aeruginosa Phage PhiKZ

Acta biochimica et biophysica Sinica, 2005
To reveal how the AT-rich genome of bacteriophage PhiKZ has been shaped in order to carry out its growth in the GC-rich host Pseudomonas aeruginosa, synonymous codon and amino acid usage bias of PhiKZ was investigated and the data were compared with that
K. Sau, S. Sau, S. Mandal, T. Ghosh
semanticscholar   +3 more sources

Crystal structure and location of gp131 in the bacteriophage phiKZ virion.

Virology, 2012
Pseudomonas phage ϕKZ and its two close relatives ϕPA3 and 201ϕ2-1 are very large bacteriophages that form a separate branch in phage classification because their genomes are very different from the rest of GenBank sequence data. The contractile tail of ϕKZ is built from at least 32 different proteins, but a definitive structural function is assigned ...
L. Sycheva, M. Shneider, N. Sykilinda, M. Ivanova, K. Miroshnikov, P. Leiman   +5 more
semanticscholar   +3 more sources

Isolation, Characterization and Genomic Analysis of a Novel Jumbo Phage, AerS_266, That Infects Aeromonas salmonicida

Microorganisms, 2023
Aeromonas salmonicida is the causative agent of septicemia in fish, and it is associated with significant economic losses in the aquaculture industry. While piscine Aeromonas infections are mainly treated with antibiotics, the emergence of resistance in ...
Vera Morozova, Igor Babkin, Yuliya Kozlova, Artem Tikunov, Tatiana Ushakova, Alevtina Bardasheva, Valeria Fedorets, Elena Zhirakovskaya, Nina Tikunova   +8 more
doaj   +1 more source

Genome packaging in EL and Lin68, two giant phiKZ-like bacteriophages of P. aeruginosa.

Virology, 2014
A unique feature of the Pseudomonas aeruginosa giant phage phiKZ is its way of genome packaging onto a spool-like protein structure, the inner body. Until recently, no similar structures have been detected in other phages. We have studied DNA packaging in P.
Olga S. Sokolova, O. Shaburova, E. Pechnikova, Alexey K. Shaytan, S. Krylov, N. Kiselev, V. Krylov   +6 more
semanticscholar   +3 more sources