Results 21 to 30 of about 434 (125)

Characterization of fluorescent proteins for STUdying the morphological rearrangements inside single bacterial cells during infection with phiKZ bacteriophage

St. Petersburg Polytechnical University Journal: Physics and Mathematics, 2022
This work deals with evaluation of key properties of some fluorescent proteins (FPs) in order to use them for observation of redistributing the target proteins between the cytoplasm and pseudonucleus forming in bacterial cell infection by bacteriophage
Antonova Daria, Zotova Anastasia, Usatykh Andrey, Morozova Natalia, Yakunina Maria   +4 more
doaj   +3 more sources

Structure of the Bacteriophage PhiKZ Non-virion RNA Polymerase Transcribing from its Promoter p119L [PDF]

Journal of Molecular Biology
Bacteriophage ΦKZ (PhiKZ) is the founding member of a family of giant bacterial viruses. It has potential as a therapeutic as its host, Pseudomonas aeruginosa, kills tens of thousands of people worldwide each year. ΦKZ infection is independent of the host transcriptional apparatus; the virus forms a "nucleus", producing a proteinaceous barrier around ...
Natalia De Martín Garrido, Kailash Ramlaul, Christopher H S Aylett   +2 more
exaly   +5 more sources

Transcription Profiling of Bacillus subtilis Cells Infected with AR9, a Giant Phage Encoding Two Multisubunit RNA Polymerases

mBio, 2017
Bacteriophage AR9 is a recently sequenced jumbo phage that encodes two multisubunit RNA polymerases. Here we investigated the AR9 transcription strategy and the effect of AR9 infection on the transcription of its host, Bacillus subtilis.
Daria Lavysh, Maria Sokolova, Marina Slashcheva, Konrad U. Förstner, Konstantin Severinov   +4 more
doaj   +2 more sources

Assessing the transcriptional landscape of Pseudomonas phage 201ϕ2-1: Uncovering the small regulatory details of a giant phage. [PDF]

Microb Biotechnol
Transcriptomic studies on jumbo phages have been limited. From a phage biology perspective, insights into their transcriptome will improve our understanding of how they regulate their infection cycle. Moreover, phage transcriptomic studies are valuable for sourcing regulatory elements which can be exploited in microbial synthetic biology to tune gene ...
Poppeliers J, Focquet M, Boon M, De Mey M, Thomas J, Lavigne R.   +5 more
europepmc   +2 more sources

Classification of Myoviridae bacteriophages using protein sequence similarity [PDF]

BMC Microbiology, 2009
Background We advocate unifying classical and genomic classification of bacteriophages by integration of proteomic data and physicochemical parameters. Our previous application of this approach to the entirely sequenced members of the Podoviridae fully ...
Ackermann Hans W, Nilsson Anders S, Mahadevan Padmanabhan, Seto Donald, Summer Elizabeth J, Darius Paul, Lavigne Rob, Kropinski Andrew M   +7 more
doaj   +2 more sources

Investigation of the therapeutic potential of bacteriophages from the genera PB1, phiKZ and LUZ24 against multidrug resistant isolates of Pseudomonas aeruginosa

, 2017
One can hear and read it everywhere: we are in a period of antibiotic-crisis. Infections, often acquired in hospitals and termed nosocomial infections, are increasingly more difficult to treat due to a diverse repertoire of resistance mechanisms developed by bacteria. The focus of this dissertation is on bacteria belonging to the so called ESKAPE-group,
Latz, Simone
openaire   +3 more sources

The world of ribonucleases from pseudomonads: a short trip through the main features and singularities

Microbial Biotechnology, Volume 14, Issue 6, Page 2316-2333, November 2021., 2021
Ribonucleases are crucial players of the post‐transcriptional regulation. Here are represented specific cases of ribonuclease‐RNA or exoribonuclease‐endoribonuclease interactions that have been uncovered so far in Pseudomonas. Summary The development of synthetic biology has brought an unprecedented increase in the number molecular tools applicable ...
Patrícia Apura, Luis G. Gonçalves, Sandra C. Viegas, Cecília M. Arraiano   +3 more
wiley   +1 more source

The human oral phageome

Periodontology 2000, Volume 86, Issue 1, Page 79-96, June 2021., 2021
Abstract Oral bacteriophages (or phages), especially periodontal ones, constitute a growing area of interest, but research on oral phages is still in its infancy. Phages are bacterial viruses that may persist as intracellular parasitic deoxyribonucleic acid (DNA) or use bacterial metabolism to replicate and cause bacterial lysis.
Szymon P. Szafrański, Jørgen Slots, Meike Stiesch   +2 more
wiley   +1 more source

Dual Active Site in the Endolytic Transglycosylase gp144 of Bacteriophage phiKZ [PDF]

Acta Naturae, 2017
Lytic transglycosylases are abundant peptidoglycan lysing enzymes that degrade the heteropolymers of bacterial cell walls in metabolic processes or in the course of a bacteriophage infection. The conventional catalytic mechanism of transglycosylases involves only the Glu or Asp residue.
O V, Chertkov, G A, Armeev, I V, Uporov, S A, Legotsky, N N, Sykilinda, A K, Shaytan, N L, Klyachko, K A, Miroshnikov   +7 more
openaire   +4 more sources

Characterization and Genomic Analysis of a Novel Jumbo Bacteriophage vB_StaM_SA1 Infecting Staphylococcus aureus With Two Lysins

Frontiers in Microbiology, 2022
The development of new antimicrobial agents is critically needed due to the alarming increase in antibiotic resistance in bacterial pathogens. Phages have been widely considered as effective alternatives to antibiotics.
Bingyan Zhang, Bingyan Zhang, Huzhi Sun, Feiyang Zhao, Qian Wang, Qiang Pan, Yigang Tong, Huiying Ren   +7 more
doaj   +1 more source