Genome landscapes and bacteriophage codon usage [PDF]
, 2007 Across all kingdoms of biological life, protein-coding genes exhibit unequal usage of synonmous codons. Although alternative theories abound, translational selection has been accepted as an important mechanism that shapes the patterns of codon usage in ...
A Eyre-Walker +60 more
core +6 more sources
A thermostable salmonella phage endolysin, Lys68, with broad bactericidal properties against gram-negative pathogens in presence of weak acids [PDF]
, 2014 Resistance rates are increasing among several problematic Gram-negative pathogens, a fact that has encouraged the development of new antimicrobial agents.
A Wohlkonig +38 more
core +9 more sources
Software-based analysis of bacteriophage genomes, physical ends, and packaging strategies [PDF]
, 2016 BACKGROUND: Phage genome analysis is a rapidly growing field. Recurrent obstacles include software access and usability, as well as genome sequences that vary in sequence orientation and/or start position.
Andy T. Ward +3 more
core +1 more source
Phage-based target discovery and its exploitation towards novel antibacterial molecules [PDF]
, 2021 The deeply intertwined evolutionary history between bacteriophages and bacteria has endowed phages with highly specific mechanisms to hijack bacterial cell metabolism for their propagation.
Hendrix, Hanne +3 more
core +2 more sources
Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort [PDF]
, 2019 Dietary interventions to manipulate the human gut microbiome for improved health have received increasing attention. However, their design has been limited by a lack of understanding of the quantitative impact of diet on a host’s microbiota. We present a
Alm, Eric J +8 more
core +1 more source
A Novel, Highly Related Jumbo Family of Bacteriophages That Were Isolated Against Erwinia [PDF]
, 2019 Erwinia amylovora is a plant pathogen from the Erwiniaceae family and a causative agent of the devastating agricultural disease fire blight. Here we characterize eight lytic bacteriophages of E.
Baltrus, David A. +7 more
core +1 more source
Characterization of modular bacteriophage endolysins from giant phiKZ related myoviridae phages OBP, 201phi2-1 and PVP-SEl [PDF]
, 2012 Peptidoglycan lytic enzymes (endolysins) of bacteriophages have a major role in bacterial lysis at the end of the phage replication cycle. These endolysins turned out to be potential antibacterial compounds to combat a broad range of Gram-positive ...
Azeredo, Joana +4 more
core
Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in Maturation [PDF]
, 2015 During virion maturation, HIV-1 capsid protein assembles into a conical core containing the viral ribonucleoprotein (vRNP) complex, thought to be composed mainly of the viral RNA and nucleocapsid protein (NC).
Cheng, N +7 more
core +1 more source
Characterization and Proteolytic Maturation of Head Proteins in a Giant Salmonella Virus [PDF]
, 2021 Giant phages are of interest for biocontrol of pathogenic bacteria, however, there is limited knowledge about their biology. We study the Salmonella phage SPN3US to better understand virion structure and function.
Scheuch, Aaron
core +1 more source
[Stucture of PhiKZ bacteriophage particles].
Voprosy virusologii, 1979 The structure of the particle of a new bacteriophage Pseudomonas phiKZ was studied. The particle of phiKZ bacteriophage was shown to have some features distinguishing this phage from all those known heretofore: a large size of the head and DNA and the presence in the head of a special structural formation named the central body.
V N, Krylov +3 more
openaire +1 more source