NOVEL APPROACH TO COMPOSITION OF BACTERIOPHAGE MIXTURES FOR ANTIBACTERIAL THERAPY
Журнал микробиологии, эпидемиологии и иммунобиологии, 2016 Aim. Evaluate antibacterial activity of an experimental mixture of phages, belonging to several well-studied species. Materials and methods. The study was carried out using a group of 55 clinical Pseudomonas aeruginosa strains of various origins, 4 mono ...
E. A. Pleteneva +10 more
doaj
Horizontal gene transfer and nucleotide compositional anomaly in large DNA viruses [PDF]
, 2007 Background DNA viruses have a wide range of genome sizes (5 kb up to 1.2 Mb, compared to 0.16 Mb to 1.5 Mb for obligate parasitic bacteria) that do not correlate with their virulence or the taxonomic distribution of their hosts.
Claverie, Jean-Michel +2 more
core +3 more sources
Characterization of tail sheath protein of giant bacteriophage φKZ Pseudomonas aeruginosa
Virology, 2009 The tail sheath protein of giant bacteriophage phiKZ Pseudomonas aeruginosa encoded by gene 29 was identified and its expression system was developed. Localization of the protein on the virion was confirmed by immunoelectron microscopy. Properties of gene product (gp) 29 were studied by electron microscopy, immunoblotting and limited trypsinolysis ...
Kurochkina, LP +4 more
openaire +3 more sources
Study of the Lysogenic Phages and Their Potential Applications in Clinical Strains of Multi-Drug Resistant Bacteria [PDF]
, 2021 Programa Oficial de Doutoramento en Bioloxía Celular e Molecular . 5004V01[Abstract] Bacteria with multiple resistance entail a global threat. In recent years, phage therapy has been widely reconsidered as an alternative to antibiotics.
Ambroa, Antón
core
Gene & Genome Duplication in Acanthamoeba Polyphaga Mimivirus
, 2005 accepted for publication in "Journal of Virology"Gene duplication is key to molecular evolution in all three domains of life and may be the first step in the emergence of new gene function.
Suhre, Karsten
core +2 more sources
PhiKZ is a bacteriophage that infects Pseudomonas aeruginosa, an opportunistic human pathogen. The phage phiKZ is known for its large genome and complex structure, making it a notable subject for structural biology studies. Among all its parts, the baseplate is the most complex. It adheres to the phage prey and triggers the genome ejection.
Seoane Blanco Mateo +3 more
openaire +2 more sources
Sequential membrane- and protein-bound organelles compartmentalize genomes during phage infection [PDF]
Many eukaryotic viruses require membrane-bound compartments for replication, but no such organelles are known to be formed by prokaryotic viruses. Bacteriophages of the Chimalliviridae family sequester their genomes within a phage-generated organelle ...
Adler, Benjamin A +26 more
core +1 more source
Regulation of Capsid Sizes of Large Tailed Bacteriophages [PDF]
, 2010 Many bacteriophages and eukaryotic viruses, which share little sequence similarities, have icosahedral protein capsids containing their genetic materials.
Hua, Jianfei
core
Viral Genome Delivery Across Bacterial Cell Surfaces [PDF]
In 1952, Hershey and Chase used bacteriophage T2 genome delivery inside Escherichia coli to demonstrate that DNA, not protein, is the genetic material.
Briani, Federica +3 more
core +1 more source
Isolation, Characterization, and Genomic Comparison of Bacteriophages of Enterobacteriales Order [PDF]
, 2019 According to CDC, every year at least 2 million people are affected and 23,000 dies as a result of antibiotic resistance in U.S. It is considered one of the biggest threats to global health. More and more bacterial infections are becoming harder to treat.
Sharma, Ruchira
core +1 more source