Results 81 to 90 of about 347 (94)

Characterisation of broad-spectrum phiKZ like jumbo phage and its utilisation in controlling multidrug-resistant Pseudomonas aeruginosa isolates

Microbial Pathogenesis, 2022
The emergence of highly virulent multidrug-resistant P. aeruginosa has become increasingly evident among hospital-acquired infections and has raised the need for alternative therapies. Phage therapy can be one such alternative to antibiotic therapy to combat multidrug-resistant pathogenic bacteria, but this requires the availability of phages with a ...
Praveen Rai, Shruthi Seetharam Shetty, Sujana Prabell, Akshatha Kuntar, Deepak Pinto, Ballamoole Krishna Kumar, Mithoor Divyashree, Juliet Roshini Mohan Raj, Ramya Premanath, Vijaya Kumar Deekshit, Indrani Karunasagar, Iddya Karunasagar   +11 more
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Interspecies migration and evolution of bacteriophages of the genus phiKZ: The purpose and criteria of the search for new phiKZ-like bacteriophages

Russian Journal of Genetics, 2010
Some properties of bacteriophages with large (200 kb and more) sequenced genomes have been compared. In contrast to other large bacteriophages from different families, bacteriophages active on pseudomonads of various species (phiKZ-like bacterio phages) have some common features, which suggests their phylogenetic relationship and independence of their ...
V. N. Krylov, K. A. Miroshnikov, S. V. Krylov, V. P. Veyko, E. A. Pleteneva, O. V. Shaburova, M. V. Bourkal’tseva   +6 more
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Assembly of phiKZ bacteriophage Inner Body during infection

Biochemical and Biophysical Research Communications
The giant myovirus phiKZ is characterised by an Inner Body (IB) structure within its capsid, crucial for orderly DNA packaging. The IB is composed of six phiKZ-specific proteins. Notably, four of these IB proteins are co-injected with DNA into the host cell, where they potentially play a role in attacking the bacterial cell.
Anna Nichiporenko, Daria Antonova, Inna Kurdyumova, Mikhail Khodorkovskii, Maria V. Yakunina   +4 more
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Genomic characterization of bacteriophage pEt-SU, a novel phiKZ-related virus infecting Edwardsiella tarda

Archives of Virology, 2019
A bacteriophage infecting Edwardsiella tarda (named pEt-SU) was isolated from freshwater collected in Chung-ju, South Korea. The whole genome of pEt-SU was 276,734 bp in length, representing the first giant phage infecting Edwardsiella reported to date. A total of 284 putative open reading frames were predicted and annotated.
Sang Guen, Kim, Sib Sankar, Giri, Saekil, Yun, Hyoun Joong, Kim, Sang Wha, Kim, Jung Woo, Kang, Se Jin, Han, Jun, Kwon, Jin Woo, Jun, Woo Taek, Oh, Se Chang, Park   +10 more
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Properties of the endolytic transglycosylase encoded by gene 144 of Pseudomonas aeruginosa bacteriophage phiKZ

Biochemistry (Moscow), 2006
Bacteriophage endolysins degrading bacterial cell walls are prospective enzymes for therapy of bacterial infections. The genome of the giant bacteriophage phiKZ of Pseudomonas aeruginosa encodes two endolysins, gene products (g.p.) 144 and 181, which are homologous to lytic transglycosylases.
K A, Miroshnikov, N M, Faizullina, N N, Sykilinda, V V, Mesyanzhinov   +3 more
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[Certain physico-chemical properties of bacteriophage phiKZ].

Molekuliarnaia biologiia, 1980
Using UV-spectroscopy and circular dichroism (CD) phi KZ bacteriophage and its DNA were investigated. From the value of optical densities in the 320--400 nm range the size of the phi KZ bacteriophage's head was determined; the diameter of phi KZ bacteriophage head was found to be equal to 1300 +/- 100 A. phi KZ bacteriophage DNA has block structure and
B V, Tiaglov, V N, Krylov, T G, Plotnikova, V E, Minaev, V I, Permogorov   +4 more
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The structural peptidoglycan hydrolase gp181 of bacteriophage φKZ

Biochemical and Biophysical Research Communications, 2008
Gp181 (2237 amino acids) of Pseudomonas aeruginosa bacteriophage phiKZ (Myoviridae) is a structural virion protein, which bears a peptidoglycan hydrolase domain near its C-terminus. This protein is supposed to degrade the peptidoglycan locally during the infection process.
Yves, Briers, Konstantin, Miroshnikov, Oleg, Chertkov, Alexei, Nekrasov, Vadim, Mesyanzhinov, Guido, Volckaert, Rob, Lavigne   +6 more
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The genome of bacteriophage φKZ of Pseudomonas aeruginosa

Journal of Molecular Biology, 2002
Bacteriophage phiKZ is a giant virus that efficiently infects Pseudomonas aeruginosa strains pathogenic to human and, therefore, it is attractive for phage therapy. We present here the complete phiKZ genome sequence and a preliminary analysis of its genome structure. The 280,334 bp genome is a linear, circularly permutated and terminally redundant, A+T-
Vadim V, Mesyanzhinov, Johan, Robben, Barbara, Grymonprez, Victor A, Kostyuchenko, Maria V, Bourkaltseva, Nina N, Sykilinda, Victor N, Krylov, Guido, Volckaert   +7 more
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[Interspecific migration and evolution of bacteriophages of the genus phiKZ: the purpose and criteria of the search for new phiKZ-like bacteriophages].

Genetika, 2010
Some properties of bacteriophages with large (200 kb and more) sequenced genomes have been compared. In contrast to other large bacteriophages from different families, bacteriophages active on pseudomonads of various species (phiKZ-like bacteriophages) have some common features, which suggests their phylogenetic relationship and independence of their ...
V N, Krylov, K A, Miroshnikov, S V, Krylov, V P, Veĭko, E A, Pletneva, O V, Shaburova, M V, Burkal'tseva   +6 more
openaire   +1 more source

Pseudolysogeny of Pseudomonas aeruginosa bacteria infected with φKZ-like bacteriophages

Russian Journal of Genetics, 2010
In this work, a final piece of evidence proving that bacteria Pseudomonas aeruginosa are capable of transition to the pseudolysogenic state after infection with phiKZ-like phages has been produced. It was shown that the decisive factor in this process is multiple infection of bacteria with bacteriophages belonging to this genus.
E A, Pletnev, S V, Krylov, O V, Shaburova, M V, Burkal'tseva, K A, Miroshnikov, V N, Krylov   +5 more
openaire   +2 more sources