Results 121 to 130 of about 886,649 (291)

Philadelphia chromosome positive AML arising from JAK2-positive myelofibrosis

Biomarker Research, 2018
Background A feature of myeloproliferative neoplasia is transforming to more aggressive and malignant myeloid neoplasia, including acute myeloid leukemia.
Marte Karen Brattås, Kyrre Lilleeng, Randi Hovland, Ingvild Jenssen Lægreid, Marta Vorland, Friedemann Leh, Øystein Bruserud, Bjørn Tore Gjertsen, Håkon Reikvam   +8 more
doaj   +1 more source

The Philadelphia Chromosome in an Unusual Case of Myeloproliferative Disease [PDF]

, 1965
Clark W. Heath, William C. Moloney
openalex   +1 more source

How I treat the blast phase of Philadelphia chromosome-negative myeloproliferative neoplasms.

Blood, 2018
The classic Philadelphia chromosome (Ph)-negative myeloproliferative neoplasms (MPNs) are a heterogeneous group of hematopoietic stem-cell diseases, characterized by activated JAK/STAT signaling and significant phenotypic mimicry, including a propensity ...
O. Odenike
semanticscholar   +1 more source

Integration of Optical Genome Mapping in the Cytogenomic and Molecular Work‐Up of Hematological Malignancies: Expert Recommendations From the International Consortium for Optical Genome Mapping

American Journal of Hematology, Volume 100, Issue 6, Page 1029-1048, June 2025.
ABSTRACT The latest updates to the classification of hematolymphoid malignancies using the World Health Organization (WHO, 5th ed.) and ICC (International Consensus Classification) criteria highlight the critical need for comprehensive and precise cytogenomic data for diagnosis, prognostication, and treatment.
Rashmi Kanagal‐Shamanna, Anna Puiggros, Isabel Granada, Gordana Raca, Katrina Rack, Mar Mallo, Barbara Dewaele, Adam C. Smith, Yassmine Akkari, Brynn Levy, Robert P. Hasserjian, Adela Cisneros, Marta Salido, Guillermo Garcia‐Manero, Hui Yang, M. Anwar Iqbal, Ravindra Kolhe, Francesc Solé, Blanca Espinet   +18 more
wiley   +1 more source

Discovery of the Philadelphia chromosome: a personal perspective [PDF]

Journal of Clinical Investigation, 2007
Almost 50 years ago, David Hungerford and I noticed an abnormally small chromosome in cells from patients with chronic myelogenous leukemia (CML). This article is a personal perspective of the events leading to the discovery of this chromosome, which became known as the Philadelphia chromosome.
openaire   +3 more sources

Umbilical cord blood transplantation from unrelated donors in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

Haematologica, 2014
There are very few disease-specific studies focusing on outcomes of umbilical cord blood transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia.
José Luis Piñana, Jaime Sanz, Alessandra Picardi, Christelle Ferrá, Rodrigo Martino, Pere Barba, Marta Gonzalez-Vicent, María Jesús Pascual, Carmen Martín, Amparo Verdeguer, Cristina Diaz de Heredia, Pau Montesinos, José-María Ribera, Miguel Sanz, William Arcese, Guillermo Sanz   +15 more
doaj   +1 more source

Chronic Granulocytic Leukaemia: Demonstration of the Philadelphia Chromosome in Cultures of Spleen Cells [PDF]

, 1965
A. S. D. Spiers, A.G. Baikie
openalex   +1 more source

Clonal chromosomal abnormalities appearing in Philadelphia chromosome-negative metaphases during CML treatment.

Blood, 2017
Clonal chromosomal abnormalities in Philadelphia chromosome-negative (CCA/Ph-) metaphases emerge as patients with chronic phase chronic myeloid leukemia (CP-CML) are treated with tyrosine kinase inhibitors (TKIs).
G. Issa, H. Kantarjian, G. Gonzalez, G. Borthakur, G. Tang, W. Wierda, K. Sasaki, N. Short, F. Ravandi, T. Kadia, K. Patel, R. Luthra, A. Ferrajoli, G. Garcia-Manero, M. Rios, S. Dellasala, E. Jabbour, J. Cortes   +17 more
semanticscholar   +1 more source

Identification of Transdiagnostic Childhood Externalizing Pathology Within an Electronic Medical Records Database and Application to the Analysis of Rare Copy Number Variation

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 4, June 2025.
ABSTRACT Externalizing traits and behaviors are broadly defined by impairments in self‐regulation and impulse control that typically begin in childhood and adolescence. Externalizing behaviors, traits, and symptoms span a range of traditional psychiatric diagnostic categories.
India A. Reddy, Lide Han, Sandra Sanchez‐Roige, Maria Niarchou, Douglas M. Ruderfer, Lea K. Davis   +5 more
wiley   +1 more source

Molecular characterization and predictors of relapse in patients with Ph + ALL after frontline ponatinib and blinatumomab

Journal of Hematology & Oncology
Background Several studies have suggested that chemotherapy-free regimens consisting of blinatumomab and a BCR::ABL1 tyrosine kinase inhibitor are highly effective in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL).
Nicholas J. Short, Hagop Kantarjian, Ken Furudate, Nitin Jain, Farhad Ravandi, Omer Karrar, Sanam Loghavi, Lewis Nasr, Fadi G. Haddad, Jayastu Senapati, Rebecca Garris, Koichi Takahashi, Elias Jabbour   +12 more
doaj   +1 more source