Results 191 to 200 of about 42,888 (218)
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The philadelphia chromosome in acute leukemia
Virchows Archiv B Cell Pathology, 1978The cytogenetics, cytology and cytochemistry, clinical findings, therapeutic response and survival of patients presenting with acute leukemia and the Philadelphia chromosome (Ph1) are briefly reviewed based upon a survey of the world literature and 16 cases seen at the University of Minnesota during the last 10 years.
Leanna L. Lindquist+4 more
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Philadelphia chromosome in eosinophilic leukemia
The American Journal of Medicine, 1965Abstract Clinical and cytogenetic findings in a patient with eosinophilic leukemia are presented. The Philadelphia (Ph 1) chromosome was found in 88.2 per cent of bone marrow cells studied by the direct method. The leukocyte alkaline phosphatase score was 25 (normal, 16 to 55).
William Dameshek+3 more
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Reciprocal translocation and the Philadelphia chromosome
Human Genetics, 1978We examined metaphases from three patients with chronic myeloid leukaemia and a typical Philadelphia chromosome with one chromosome 9 as the recipient to determine whether the 9q+22q- translocation is reciprocal. Good quality G-banded photographs of the chromosomes concerned were subjected to light absorption density analysis.
Brenda M. Page, Jessie L. Watt
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Silent Philadelphia Chromosome
Cancer Genetics and Cytogenetics, 2000In this paper, a patient is described who presented with peripheral blood and bone marrow features uncharacteristic of chronic granulocytic leukemia, which proved to be Philadelphia (Ph) chromosome-positive by metaphase and interphase cytogenetic analyses but lacked the p210 type of BCR/ABL fusion gene mRNA product by two different sensitive RT-PCR ...
János A. Vass+5 more
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The occurrence of the Philadelphia chromosome in essential thrombocytosis
Human Genetics, 1981The Philadelphia chromosome, assessed with banding techniques, was detected in 98.3% of bone marrow cells of a 46-year-old black female presenting with essential thrombocytosis. The patient has been followed for the past two years with no signs of chronic myelocytic leukemia.
Barathur R. Rajendra+5 more
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Myeloblastenleukämie mit Philadelphia-Chromosom
Klinische Wochenschrift, 1967Bei einem fruher wegen Larynx-Carcinoms mit Rontgenstrahlen behandelten Mann trat 3 Jahre spater eine Myeloblasten-Leukamie auf. Bei den cytogenetischen Untersuchungen wurden neben dem Vorkommen des Philadelphia-Chromosoms weitere Chromosomenaberrationen in der Gruppe F und G sowie eine Polymorphie des Y-Chromosoms gefunden.
Helmut Martin, M. Hussein Khan
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The Philadelphia or Short Y Chromosome
JAMA: The Journal of the American Medical Association, 1974To the Editor.— In the case of the patient with erythroleukemia and Philadelphia (Ph') chromosome described by Pacheco et al (226:787, 1973), the sex of the patient is not stated. Since erythrocytic glucose-6-phosphate dehydrogenase deficiency was also present, we suspect that the patient was a man.
Michael P. Corder, Eugene P. Flannery
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Acute Myeloid Leukaemia with the Philadelphia Chromosome
Scandinavian Journal of Haematology, 1977A case report of serial chromosome studies on a 26‐year‐old male with acute myeloid leukaemia (AML) is presented. The classic Philadelphia chromosome (Ph1) transloca‐tion, t (9; 22) was found in 77 % of the metaphases at diagnosis and in 100 % in relapse; during a 3‐month remission period the cytogenetic picture was normal or the Ph1 was present in a ...
Felix Mitelman+2 more
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The Philadelphia Chromosome and Some Others
Annals of Internal Medicine, 1964Excerpt The appearance elsewhere in this issue of three papers on chromosome studies in chronic granulocytic leukemia (CGL) has suggested that some sort of stock-taking is in order concerning the p...
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PHILADELPHIA-CHROMOSOME-POSITIVE PRELEUKÆMIC STATE
The Lancet, 1972Abstract Serial chromosomal analyses were performed in an untreated patient who demonstrated little or no haematological disease for over 5 years before the development of overt blastic leukaemia. The Philadelphia chromosome (Ph') was present in a small percentage of marrow cells during the preleukaemic period.
George P. Canellos+1 more
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