Results 241 to 250 of about 100,585 (270)

Studies of the Philadelphia Chromosome.

Annals of Internal Medicine, 1964
Excerpt An abnormal chromosome called "Philadelphia" or Ph1has been demonstrated in the metaphase nuclei of hematopoietic cells of patients with chronic myelocytic leukemia.
S. N. Swisher, K. O. Goh
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Essential thrombocythaemia and the Philadelphia chromosome

British Journal of Haematology, 1988
Six adult patients presented with clinical features of essential thrombocythaemia. Five of the patients, although Ph‐positive, have maintained these features without evidence of leukaemia; in one case for 9 years. A sixth patient developed leukaemic blast crisis following a persistently high platelet count over 4 years.
Peter E. Hollings, Christine M. Morris, Susan A. Archer, M. E. J. Beard, D. C. Heaton, Peter H. Fitzgerald, Ingrid Rosman, C. J. Newhook   +7 more
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The philadelphia chromosome in acute leukemia

Virchows Archiv B Cell Pathology, 1978
The cytogenetics, cytology and cytochemistry, clinical findings, therapeutic response and survival of patients presenting with acute leukemia and the Philadelphia chromosome (Ph1) are briefly reviewed based upon a survey of the world literature and 16 cases seen at the University of Minnesota during the last 10 years.
Leanna L. Lindquist, Clara D. Bloomfield, Richard D. Brunning, Peter F. Coccia, Jorge J. Yunis   +4 more
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Philadelphia chromosome in eosinophilic leukemia

The American Journal of Medicine, 1965
Abstract Clinical and cytogenetic findings in a patient with eosinophilic leukemia are presented. The Philadelphia (Ph 1) chromosome was found in 88.2 per cent of bone marrow cells studied by the direct method. The leukocyte alkaline phosphatase score was 25 (normal, 16 to 55).
William Dameshek, Kosmas A. Kiossoglou, Hans Gruenwald, W. J. Mitus   +3 more
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Reciprocal translocation and the Philadelphia chromosome

Human Genetics, 1978
We examined metaphases from three patients with chronic myeloid leukaemia and a typical Philadelphia chromosome with one chromosome 9 as the recipient to determine whether the 9q+22q- translocation is reciprocal. Good quality G-banded photographs of the chromosomes concerned were subjected to light absorption density analysis.
Brenda M. Page, Jessie L. Watt
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Silent Philadelphia Chromosome

Cancer Genetics and Cytogenetics, 2000
In this paper, a patient is described who presented with peripheral blood and bone marrow features uncharacteristic of chronic granulocytic leukemia, which proved to be Philadelphia (Ph) chromosome-positive by metaphase and interphase cytogenetic analyses but lacked the p210 type of BCR/ABL fusion gene mRNA product by two different sensitive RT-PCR ...
János A. Vass, Karoly Szuhai, László Pajor, Molnár L, Pál Jáksó, László Kereskai   +5 more
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The occurrence of the Philadelphia chromosome in essential thrombocytosis

Human Genetics, 1981
The Philadelphia chromosome, assessed with banding techniques, was detected in 98.3% of bone marrow cells of a 46-year-old black female presenting with essential thrombocytosis. The patient has been followed for the past two years with no signs of chronic myelocytic leukemia.
Barathur R. Rajendra, Demetra V. Rose, Michael J. Nissenblatt, Leonard J. Sciorra, Gary Gartenberg, Ming-liang Lee   +5 more
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Myeloblastenleukämie mit Philadelphia-Chromosom

Klinische Wochenschrift, 1967
Bei einem fruher wegen Larynx-Carcinoms mit Rontgenstrahlen behandelten Mann trat 3 Jahre spater eine Myeloblasten-Leukamie auf. Bei den cytogenetischen Untersuchungen wurden neben dem Vorkommen des Philadelphia-Chromosoms weitere Chromosomenaberrationen in der Gruppe F und G sowie eine Polymorphie des Y-Chromosoms gefunden.
Helmut Martin, M. Hussein Khan
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The Philadelphia or Short Y Chromosome

JAMA: The Journal of the American Medical Association, 1974
To the Editor.— In the case of the patient with erythroleukemia and Philadelphia (Ph') chromosome described by Pacheco et al (226:787, 1973), the sex of the patient is not stated. Since erythrocytic glucose-6-phosphate dehydrogenase deficiency was also present, we suspect that the patient was a man.
Michael P. Corder, Eugene P. Flannery
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The Philadelphia Chromosome and Some Others

Annals of Internal Medicine, 1964
Excerpt The appearance elsewhere in this issue of three papers on chromosome studies in chronic granulocytic leukemia (CGL) has suggested that some sort of stock-taking is in order concerning the p...
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